Creating a genome-wide CRISPR interference functional genomic library in Candida albicans to study fungal gastrointestinal colonization

Candida albicans is an important human fungal pathogen and commensal member of the microbiota. It colonizes the skin, gut, and reproductive tract of most healthy individuals without complications – a state known as commensalism. However under conditions that weaken the immune system, antibiotic use, and damage to the lining of the gut, C. albicans can […]

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Pharmacology of GBA1 Chaperones

Mutations in the enzyme glucocerebrosidase (GBA1) are the most common genetic risk factor for development of Parkinson’s disease (PD). PD is characterized by the buildup of abnormal protein deposits in the brain, followed by progressive loss of neurons and behavioural symptoms. Numerous studies have noted a correlation between reduced GBA1 activity and increased levels of […]

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Sea Cucumber as a source of active ingredient for cosmeceutics

The research project involves studying how extracts from sea cucumbers can be used in skin care products. Sea cucumbers are marine animals known for containing natural substances that might be beneficial for skin health, like slowing down skin aging or lightening skin tone. The project has two main goals: first, to make sure these sea […]

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Phytofiltration de PFAS par des saules à croissance rapide

Le présent projet de recherche porte sur l’étude de la distribution de contaminants émergents, soit les substances per- et poly-fluoroalkylées (SPFA, ou PFAS en anglais), dans les plantes, plus particulièrement les saules à croissance rapide, lorsqu’irrigués avec des eaux contaminées ou du lixiviat de lieux d’enfouissement. Les PFAS sont une famille de composés chimiques synthétiques […]

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2 Billion Tree program

NBAPC will plant 10,537 trees and shrubs in 2024 along the Wolastoq and the Nashwaak River Watersheds. In year one, NBAPC will hire a staff member and begin preparation for planting in year two. In year two, they will plant a total of 10,537 trees and shrubs across five sites. Tree planting will be completed […]

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rTMS for post-covid-19 condition: A sham-controlled case series involving iTBS-300 and iTBS-600

The objective of the “rTMS for post-covid-19 condition: A sham-controlled case series involving iTBS-300 and iTBS-600” project is to determine the efficacy, feasibility, and tolerability of several iTBS variants (iTBS-300, iTBS-600) and sham stimulation in PCC patients. Secondarily, the aim is to examine signs of improvement in cognitive, affective, and functional symptoms following each iTBS […]

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Environmental Stewardship Coordinator

Members of the District of Lakeland Environmental Advisory Committee (EAC) have been conducting environmental sampling since 2011 on four lakes within the District of Lakeland, Saskatchewan, particularly Emma Lake. The primary goal of the program is to collect consistent water quality data, building a database that could be used for public environmental stewardship education. The […]

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Quantitative scanning electron microscopy characterization to determine if microfibrillated cellulose is considered a nanomaterial in food, food-contact and cosmetic regulations

The proposed project will use microfibrillated cellulose (MFC) from the University of Maine Process Development Center (UMaine MFC) as a reference material to develop a robust dispersion, sample preparation, image capture, and image analysis methodology to determine whether it is considered a nanomaterial under different regulatory frameworks. The methodology will employ scanning electron microscopy (SEM), […]

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Partnered health system innovation for people who use drugs

“Health System Innovation for People Who Use Drugs (PWUD)” is an implementation project that will help translate research into co-designed supports. This project is a collaboration between individuals with lived and living experience of currently illegal (i.e., non-alcohol, non-tobacco, non-cannabis) drug use and health system partners in Edmonton, AB – Boyle Street Community Services (BSCS) […]

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