Développement d’un modèle de cécité corticale chez la souris

Les déficiences visuelles, dues à des lésions cérébrales, touchent les nouveau-nés et les personnes âgées des pays industrialisés, en raison de l’allongement de la vie. Ce projet de recherche va utiliser la souris pour étudier la récupération des fonctions visuelles après un AVC. Il va explorer les modifications neuronales et de connectivité grâce à des […]

Read More
Investigation of antifungal properties of thiazolidine derivates

Infections, caused by the Candida species have emerged as a significant global health concern. These diseases can range from superficial to life-threatening, affecting various body parts. However, the effective management of Candida infections is increasingly challenged by the growing issue of drug resistance.Focusing on that problem, our research project aims to investigate the antifungal properties […]

Read More
La combinaison de la cyclosporine 0.09% et de la thérapie IPL dans le traitement de la sécheresse oculaire chez les porteurs de lentilles cornéennes symptomatiques : essai clinique randomisé contrôlé par simulacre

La sécheresse oculaire est un problème très répandu qui peut causer des symptômes significatifs et nuire à la santé de la surface de l’oeil. Les porteurs de lentilles de contact sont particulièrement sujets à souffrir de sécheresse oculaire. Ce projet va étudier l’impact de la combinaison de deux traitements différents sur les gens qui portent […]

Read More
Blood and Nasal Biomarkers of Cat-SPIRE Efficacy

The Cat-SPIRE vaccine reduces symptoms in those who suffer from cat allergy. Two interns will work on complementary projects that will evaluate blood and nasal biomarkers of Cat-SPIRE efficacy. One trainee will examine changes to the DNA in special immune cells called dendritic cells, isolated from blood. The other trainee will examine markers of inflammation […]

Read More
Feasibility, validity, and reproducibility of wearable sensing technologies to assess mobility in hospitalized older adults

Following hospitalization, many patients do not return to their pre-hospitalization level of health. In older patients, the time spent in a hospital bed leads to mobility impairments. We propose to use wearable sensing device to register the time spent by hospitalized older adults in the bed and walking. This information will help to better identify […]

Read More
Identification and Characterization of Antioxidant Activity in Canadian Wild Plants: A New Horizon in Wellness Industries

The proposed research project aims to explore and study natural substances called antioxidants that can be found in plants native to Canada. Antioxidants from plants are natural products that promote wellness by protecting our bodies from harmful molecules called free radicals. Certain plants that flourish under the conditions found in the Canadian prairies are likely […]

Read More
Optimization of new inhibitors of type 2 serine proteases as anti-influenza agents

The proposed project aims at optimizing new antivirals to fight influenza. Current antivirals, which target proteins of the virus, suffer from severe resistance owing to mutations in the virus. Our group has identified some enzymes in the human lung that are critical for the maturation of the influenza virus. By blocking these enzymes, we expect […]

Read More