Développer des outils pour cribler les activités antivirales d’alcaloïdes végétaux.

La pandémie de coronavirus a été un rappel brutal des dommages que peuvent causer les maladies virales. Actuellement, il existe des traitements antiviraux contre le SARS-CoV-2, mais l’émergence continue de variants demande une diversification constante de ces molécules. À cela, s’ajoute à un risque d’exposition aux agents infectieux déjà augmenté en raison de la mondialisation […]

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Development of an analytical framework for multiple cellular (omics) responses of Canadian aquatic species exposed to different environmental conditions to guide the management of biodiversity, fisheries and aquaculture.

Canadian ocean and freshwater systems currently undergo rapidly changing disturbances that threaten high-value aquatic species such as shrimps and fishes, even in Marine Protected Areas. Whilst biologists gathered a large amount of knowledge (and data) about the responses of aquatic animals in such disturbed environments, our current understanding is often limited to individual single-layer levels […]

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Optimization of Myelin Water Imaging

The purpose of this research project is to optimize a magnetic resonance technique designed to measure myelin in brain and spine. This technique holds great promise for diagnosis and management of neurodegenerative diseases as well as abnormal brain development. The finalgoal ofthe project is to have a magnetic resonance protocol which could be offered as […]

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Development of an optical sports monitoring sensor and method for non-invasive evaluation of muscle metabolic fitness and function in elite athletes – Part 2

Currently, elite athletes and their coaches rely on the subjective self-awareness and measurement of muscle force, heart rate, and the amount of blood lactic acid level to monitor body fitness and athletic performance. These methods, however, are not ideal and always reliable due to subjective errors, technological limitations and individual confounding factors that limit the […]

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Étude de la qualité, de la stabilité et de la circulation des antibiotiques utilisés dans la prise en charge des survivantes de violences sexuelles en République démocratique du Congo

Les actes de violence sexuelle (VS) sont encore largement répandus dans le monde et continue d’aggraver des situations déjà précarisées par des conflits armés et des catastrophes naturelles. La République Démocratique du Congo (RDC) connait cette triste réalité. Les femmes victime de ces atrocités se retrouvent parmi toutes les tranches d’âges et requièrent des soins […]

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Effect of exercise training on the human skeletal muscle proteome, phosphoproteome, and proteodynamics

Generally, resistance exercise increases muscle mass and strength, whereas endurance exercise increases the capacity to use fuels and fatigue resistance. In both cases, skeletal muscle translates the physical and biochemical stresses of exercise into morphological and metabolic adaptations, with the adaptations improving one’s ability to perform the corresponding type of exercise. This concept is known […]

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The use of eDNA as a tool to augment gill net sampling for fish community monitoring

Traditional monitoring of fish community using gillnets is a well-established standard but comes with biases associated with selectivity of net sizes as well as significantly mortality of caught fish. Environmental DNA (eDNA) is rapidly becoming the new standard in fish and wildlife monitoring because it is less susceptible to biases, and it eliminates animal mortality. […]

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Synthèse et caractérisation biochimique de dendrimères fluorescents

En raison de la présence de la Barrière Hémato-Encéphalique (BHE), le cerveau est considéré comme l’un des organes les plus difficiles à cibler pour une action pharmacologique. Les pathogènes neurotropes, en revanche, ont été démontrés capables de traverser cette barrière et d’infecter les tissus cérébraux à travers l’endothélium microvasculaire cérébral. Ce projet repose sur l’hypothèse […]

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Population size and predation risk of Leach’s Storm-petrel (Hydrobates leucorhoa) nesting at Île-Bonaventure, Québec

Leach’s Storm-petrel are a small, wide-spread, pelagic seabird that have recently undergone population declines, they are listed as Vulnerable by the IUCN and Threatened in Canada. Populations of Leach’s Storm-petrel on the Gaspé Peninsula are very small and known from just two locations. Île Bonaventure, a migratory bird sanctuary and part of the Parc National […]

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NL Seafood Sector Organic Waste Inventory Assessment

The purpose of this study is to identify sources, locations, and quantities of unutilized marine biomass materials that are available within the province, and to identify opportunities for improving the industry’s utilization of these materials. The inventory assessment will focus on unutilized marine biomass materials generated by the seafood processing sector from landings of commercially […]

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