Molecular mechanisms of nuclear reformation after mitosis

The project aims to understand the molecular mechanisms by which the Ankle2 protein functions to allow nuclear reformation after mitosis. This process is frequently disrupted in cancer cells, which induces an innate immune response that could be exploited in therapies. A multidisciplinary approach in the Drosophila model will be used.

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Deciphering the immunosuppressive functions of viral glycoproteins

Embedded in the surface of a virus, are different types of proteins that the virus uses to enter a host cell. These so-called viral glycoproteins are pivotal targets of the host antibody response to fight a viral infection. In recent decades, it has become clear that certain viral glycoproteins have evolved clever ways to suppress […]

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Targeting mitochondrial efficiency to promote resilience of dopamine neurons

Parkinson’s disease (PD) is a devastating neurodegenerative disease impacting the nervous system and resulting in a wide range of symptoms including characteristic motor impairments such as tremor, slowed movement and muscle rigidity. It is an age-related disease affecting 1% of the population over the age of 60. Although symptomatic treatments are available, there are no […]

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Biobased Polyurethane Composites Comprised of Lignin derivatives

Polyurethanes are an important class of synthetic polymers with widespread applications in consumer products. The origins of most of these products are derived from petrochemicals, and these traditional polymers are non-degradable and have limited recyclable potential. There is a need in this industry to endorses the practice of conserving resources, minimizing the environmental, health impacts […]

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Effects of Probiotics on Anxiety and ADHD in Children

The Probiotics and Mental Health Research Lab in the Psychology Department at Acadia University is currently involved in exciting and innovative research examining the benefits that probiotics (a type of beneficial bacteria found in the human digestive tract as well as in certain foods) may provide to individuals living with psychological conditions such as anxiety, […]

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Analysis of lipids extracted from soil exposed to decomposing human remains

Decomposition is the dynamic process whereby a compound is disintegrated into its elementary constituents through physical, chemical and biological mechanisms. Matrices associated with decomposing human remains, such as soil, are an omnipresent source of physical evidence in forensic casework. Previous research has already emphazied the use of these matrices to evaluate their potential to capture […]

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Microbiome-endocannabinoidome role in response to prebiotic and probiotic interventions in a Murine Model of Diet-Induced Metabolic Syndrome

Probiotics could help prevent or treat metabolic-related conditions such as dyslipidemia or Type 2 Diabetes. Combination of probiotics with prebiotic fibers could potentiate the positive effect of these treatments. Our hypothesis is that probiotic strains, coupled with brown algae prebiotic fibers, may hold potential for modulating lipid metabolism, which might represent an interesting avenue for […]

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Mode of action of organic plant-growth stimulant in tomato trials

This proposed project will investigate potential modes of action of novel plant biostimulants on tomato plants. This will include changes in the plant growth rates and potential plant gene activation as it relates to the biostimulant treatment. It will also investigate changes in the microorganism profile in the root zone of biostimulant treated plants. In […]

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Acceleration of improvement in health and production of mink through genomics and machine learning

The project will examine of population genomics, application of genomic selection, and identification of genes underlying economically important traits which are vital steps for the development of selection program. Consequently, this will have an impact on the economic viability of mink producers due to targeted genomic breeding strategies and the use of biomarker-assisted selection. Such […]

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L2M MITACS – Improving the Storage Stability of Research Grade Proteins using Super- Hydrophilic Sponges

The proposed research project seeks to explore the application of foam-like inserts to improve the shelf life of commonly used proteins. Many commercial proteins are used in a variety of applications such as food production, pharmaceuticals, and scientific research. These proteins must be stored at sub-zero temperatures as they are prone to degradation at higher […]

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Discovery of microbial enzymes for biodegradation of plastic polymers

In an effort to reach zero waste in Canada by 2030, this work is dedicated to the discovery of microbes with enzymatic capabilities to biodegrade plastic. A library of microbes (bacteria and fungi) isolated from a range of marine environments will be screened for unique and novel plastic biodegrading activities. Preferred microbes will be selected […]

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