Targeting a complement serine protease in vascular disease

In spite of major advances in our knowledge and better treatments, heart attacks, strokes and blood clots in the legs and lungs, continue to major causes of disability and death. Recent studies reveal that a protein (a so-called “serine protease”) in our blood, when increased, may heighten the risk of excess blood clot formation in […]

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Deep Learning with Big Data for Innovation Acceleration

XLScout uses Natural Language Processing (NLP), Machine Learning (ML), and Innovation/Scientific principles to deliver actionable intelligence and accelerate innovation by analyzing large patent and research databases. The company is eliminating the pain of manually going through document and quickly providing relevant information to support data-driven strategic decisions. Presently XLScout hosts a data vault of over […]

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Improved inhibitors of HIV infection

ViroCarb has identified a new class of HIV inhibitors against a new therapeutic target on the HIV envelopeprotein gp120, present in all HIV, including drug resistant strains. The objective of this internship is to conduct screening studies of libraries, designed based on this new chemical class for optimal efficacy and drug-like properties, using methods previously […]

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Effet de la présence de feuillus sur le succès de l’éclaircie pré commerciale opérée sur sols tourbeux

La compétition entre les arbres pour les ressources du milieu s’intensifie à mesure que la forêt se développe. Le traitement sylvicole alors utilisé afin de réduire la compétition est l’éclaircie précommerciale (EPC), qui vise la libération et la redirection des ressources vers les essences d’arbre désirées. Dans la forêt boréale, le couvert végétal au sol […]

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Functional investigation of the dynamics of TERRA in cancer cells

The research project is focused on the study of TERRA (Telomeric Repeat containing RNA) dynamics in cancer cells to understand the relationship between cancer and telomere. TERRA long noncoding RNAs have been proposed to play important roles in telomere biology. However, the dynamics of TERRA molecules are yet to be elucidated. Indeed, in human cells, […]

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Analytical Characterization of JZP-341 (Higher Order Structure)

York University and Jazz Pharmaceuticals are undertaking a project to accelerate development of their Leukemia drug candidate. The project will take advantage of unique technologies developed at York by Drs. Wilson and Krylov, Millisecond Hydrogen Deuterium eXchange (msHDX) mass spectrometry and Kinetic Capillary Electrophoresis (KCE), to provide a high-detail picture of Jazz Pharmaceutical’s candidate, including […]

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Investigating social-ecological enabling conditions for the revitalization of Indigenous clam management systems in an urban context

The general objective of the proposed activity is to increase the future productivity of Burrard Inlet and the contribution of seafood to the diet of Tsleil-Waututh Nation (TWN) members in support of the TWN Cumulative Effects Monitoring Initiative. Specifically, we propose to identify the primary environmental drivers of clam productivity and species composition in Burrard […]

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Understanding the threats: plastic pollution and migrating shorebirds

Discarded plastic is a significant environmental contaminant. Plastic pollution is found in marine and freshwater systems and affects a substantial number of aquatic species around the world, either by entanglement or ingestion of small pieces (i.e. microplastics). These plastic debris release dangerous chemicals with unknown toxic effects for species that rely on marine environments to […]

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Understanding the threats: plastic pollution and migrating shorebirds – Year two

Discarded plastic is a significant environmental contaminant. Plastic pollution is found in marine and freshwater systems and affects a substantial number of aquatic species around the world, either by entanglement or ingestion of small pieces (i.e. microplastics). These plastic debris release dangerous chemicals with unknown toxic effects for species that rely on marine environments to […]

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