This project will engage seniors, family members, and care staff, a total of 53 participants in a long-term care home to adopt a new technolopgydevice, Tochie for familyconnection. Participants will use the assistive audio speakers named Tochie over one month. Ongoing support and assistance will be provided to all participants during the one month to […]

Huntington’s disease (HD) is a genetic neurodegenerative disease characterized by cognitive, motor, and psychiatric disturbance ending in death 15 to 20 years after the onset of the first symptoms. The genetic predictability of HD makes it potentially the most tractable of the neurodegenerative diseases for early intervention, with the optimum time for the introduction of […]

Bats are fascinating animals that provide many ecological services by regulating insect populations. They can eat about 600 insect per hour! Since the introduction of white-nose syndrome in 2006, bat populations in North America have become increasingly threatened. This fungal disease has caused dramatic decreases in many bat populations. Without a cure for white-nose syndrome, […]

Dental light-curing units (LCUs) are used every day in most dental offices. If this LCU is misused, this dental work can fail prematurely causing pain, post-operative sensitivity, pulpal death, and economic hardship. In Canada, dental curing lights are Class 1 medical devices, and Health Canada does not test dental curing lights before they are used […]

By growing stem cells in the right conditions, we are able to create miniature brain tissue structures called organoids. These organoids have many properties that make them similar to adult brains, which makes them a valuable tool to study how brain tissues might be affected by drugs, or how brain diseases like epilepsy can occur. […]

Irreversible, progressive, and incurable neurodegenerative diseases, such as Alzheimer’s disease (AD) or Parkinson’s disease (PD), constitute severe challenges for the modern and, in particular, for the healthcare system. Recent reports suggest that worldwide >50 Mio. people and >10 Mio. people are living with AD or PD, respectively. Both diseases are related to protein misfolding and […]

Elevated levels of stress hormones (i.e. cortisol) provide a potential mechanism by which substrate condition affects larval development and survival in the endangered white sturgeon. The possibility that stress hormones mediate larval response to substrate conditions will be investigated by artificially elevating cortisol levels and identifying effects on larval physiology. Cortisol levels of wild caught […]

Minke whales are common in the North Atlantic, but there are huge gaps in scientific knowledge about the species. Through collaboration with Mériscope, we will attach satellite tags to minke whales that feed in the St Lawrence Estuary (SLE) in the summer to track where they migrate throughout the rest of the year. At the […]

Cropland soils are important sources of nitrous oxide (N2O), which is one of greenhouse gases. In soils, N2O is produced through nitrification and denitrification processes. Therefore, it may be possible to reduce N2O production by using biochar and nitrification inhibitors (NI). Biochar is known to decrease N2O production through biological and physico-chemical interaction with soil […]

Impaired empathy and social skills lead to severe social consequences and influence the development and treatment of several psychiatric disorders. Furthermore, empathy has been shown to play a crucial role in moral and prosocial behavior. Recently, a revamped interest for psychedelic compounds has invested the medical research community. For instance, psilocybin is a psychedelic compound […]

Chemotherapy drugs target and kill rapidly-dividing cells located closest to blood vessels, but do not penetrate deep into the tumor. Limited drug distribution in tumors is an important cause of drug resistance. A method to increase tumor drug delivery and combat resistance is the subject of this proposal. To counteract chemotherapy resistance, the use of […]

The aim of this research project is to observe the difference in function between the dominant and non-dominant lower limb in elite youth hockey athletes. Further, to observe how this difference is altered when the athlete is fatigued. Reducing or eliminating limb imbalances is thought to have a positive outcome on reducing injury risk, ensuring […]