Our objective is to create, evaluate, and sustain an evidence-based leadership intervention to foster employee wellbeing. Based on the leadership development and organizational change literatures, I am proposing to conduct two studies at a provincial-based financial institution. The first study will explore the beliefs and opportunities to model health behaviours in the workplace and serves […]

L’incapacité de travail constitue un enjeu majeur depuis plusieurs décennies en raison de l’escalade du fardeau social et économique. Pour arriver à assurer la congruence entre les capacités d’un individu et les exigences de son milieu de travail, plusieurs acteurs sont impliqués dans le processus de réadaptation au travail (agent payeur, clinique de réadaptation, employeur, […]

The purpose of the present study is to scientifically evaluate the physical demand associated with the safe operation of a snowmobile under typical (normal) riding conditions experienced by North American snowmobilers. We will quantify the physical demand of snowmobile riding and compare this to national recommendations for the promotion of health and fitness, as well […]

Schizophrenia is a serious and severe mental disorder of yet unknown etiology. Genetic, developmental and environmental factors have all been implicated in the emergence of the disorder. In particular, abnormalities in both morphology and volume of the hippocampus have been implicated in the underlying mechanisms contributing to the emergence of psychosis in schizophrenia and in […]

L’utilisation des Brettanomyces au sein des fermentations alcooliques est en forte croissance depuis plusieurs années. Traditionnellement considérée comme un contaminant, cette levure se retrouve désormais au centre de nombreux produits fermentés, particulièrement dans l’industrie brassicole. Jusqu’à maintenant, les Brettanomyces sont utilisées principalement en fermentation secondaire, afin d’affiner les produits. Par contre, peu d’informations sont connues […]

Forests provide habitat to more than 65% of terrestrial biodiversity, yet are being eliminated or greatly simplified at an alarming rate under global change (GC). Current forestry practices tend to favour a handful of species, without considering resilience of resulting forests to GC. During the past two decades, studies have investigated the complex relationships between […]

CD36 is a receptor present on the surface of a great variety of cells. On macrophages, specialized cells of our immune system, CD36 can as an environmental sensor. In fact, macrophages can undertake multiple activity profiles depending on their environment. M1 macrophages are formed in response to bacterial attack for example, and promotes inflammation. M2 […]

The goal of my research is to study the effect of stretch on the release of the energy-carrying molecule adenosine triphosphate (ATP) in the lung. In response to physical forces, cells release ATP as a signaling molecule to regulate various pulmonary functions, such as the secretion of surfactant, which helps us to breathe. However, little […]

Decreased brain volume in frontal regions is a prominent feature of schizophrenia and has been linked to impairments in psychological and social functioning. These impairments persist over the lifespan, with approximately 64% of individuals experiencing severe social disability 15-years after illness onset. Finding ways to overcome barriers to better functioning is of utmost importance to […]

Pulmonary hypertension or elevated blood pressure in the lung caused by left heart diseases such as mitral valve stenosis is classified as Group 2 under the World Health Organization pulmonary hypertension classification system. Group 2 pulmonary hypertension is the most common type of pulmonary hypertension, but currently there is no approved therapies for this disease. […]

Among Drosophila species, volatile organic compounds are key for host- and mate-finding behaviour. Recently, it was discovered that a single olfactory receptor channel (Or69a) in D. melanogaster that is tuned to both host odours and sex pheromones (Lebreton et al. 2017). Phylogenic analysis suggests this receptor is conserved across all Drosophila species; however, Or69a is […]

My project focuses on using a chemistry-based approach to improve the delivery of an insoluble compound, gambogic acid (GA). GA is a natural product that has great potential as an anti-inflammatory drug. However, its clinical application has been limited due to the poor aqueous solubility and significant toxicity against red blood cells. I am currently […]