Density functional theory (DFT) assessment of new ligand designs for catalytic olefin polymerization – depolymerization

The upcoming research internship will explore hypothetical molecules derived from pyridine, which could be integrated in ligands for olefin polymerization and, potentially, depolymerization. Olefin polymerization is a catalytic process by which polyethylene and polypropylene are manufactured using catalysts incorporating unique ligand frameworks. This computational study aims to 1) determine the best ligand design for molecules […]

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Development of Climate and Infrastructure Forensic Analysis Systems: A BayesianPerspective

This project will upgrade the Climate and Infrastructure Forensic Analysis System (CIFAS), originally developed to characterize snow- and permafrost-related impacts to ground transportation and mine access roads in the Canadian North. My first objective is to enhance the analytical capacity of CIFAS by improving its ability to quantify uncertainties associated with empirical knowledge used to […]

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L2M-Materiax AI

This project will explore the market potential of a new technology that uses advanced artificial intelligence, powered by both classical and quantum methods, to help companies discover new materials faster and more efficiently. The intern will work closely with mentors and industry experts to identify which industries can benefit the most from this innovation and […]

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L2M – Probes to Enable Imaging Small Molecules in Cells

Cellular imaging enables the study of diseases in myriad ways, consequently impacting human health. Through visualizing individual cells, clinicians are able to diagnose diseases and scientists are able to develop drugs to treat them. There are many powerful tools to visualize cells, including fluorescence and electron microscopy. However current common imaging techniques fall short for […]

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L2M – Approaches to Novel Anticancer Therapeutics via MRCK Inhibition

MRCK is an enzyme that has shown promise as a target for the development of new drugs to treat several aggressive cancers, including glioblastoma (GBM) and high grade serous ovarian cancer (HGSOC). BDP9066 is a highly potent and selective inhibitor of MRCK reported first in 2018. Despite excellent activity profile, BDP9066 is not a realistic […]

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