Clinical utility evaluation of a NGS based assay for the detection of genetic modifiers in families with reduced penetrance or uncertain copy number variants

There is increasing evidence that multiple genetic variants within a patient can compound their effects, resulting in a more severe clinical phenotype in comparison with the clinical manifestations in individuals with single genetic variation. In this study, we aim to examine the clinical utility of a massively parallel sequencing technique to identify clinically relevant secondary […]

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Restoring bacterial sensitivity to aminoglycosides antibiotics

Bacterial resistance to aminoglycoside antibiotics is a major public health problem. The WHO (World Health organization) has highlighted the urgent need to find new treatments to fight multidrug resistance MDR bacteria, as actual drugs are less effective or inactive. This research project aims to develop new chemical compounds to restore bacterial sensitivity to antibiotics currently […]

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Data Analytics Models for FreshBooks’ Customers’ Engagement

An organization that can effectively understand its specific customers’ needs will be able to follow the best communication approach and accurately measure engagements. A data-driven framework based on the customer’s digital behavior, historical data, will be developed to identify specific customer segmentation and used to find optimal next best action to enhance customer experience by […]

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Nonlinear photonics applications of tellurite-coated silicon nitride waveguides

This project is about integrated photonics. Similar to integrated electronics, both have many applications in our lives such as in communications, biosensing, security, display and imaging. Interestingly, photonic circuits are poised to replace electronics circuits in telecommunications and data centers. Compared to electronics, they will reduce cost, increase speed and bandwidth of the future Internet […]

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Fundamental Studies of Aerobic Membrane Bioreactor under Short Sludge Retention Time Conditions for Municipal wastewater treatment

Conventional wastewater treatment processes consume a large amount of energy and produce around 32% of municipal greenhouse (GHG) emissions. Thus, advanced wastewater treatment technologies with low energy consumption and GHG emissions are highly desirable for environmental protection. Aerobic membrane bioreactor (AeMBR) has been widely used for municipal and industrial wastewater purification. However, the AeMBR technology […]

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Mathematical Modelling and Electrochemical Impedance Spectroscopy for Degradation Monitoring of Proton Exchange Membrane Water Electrolyzers

Water electrolysis plays a vital role in clean energy generation by producing hydrogen from water. Proton Exchange Membrane Water Electrolyzers represent a novel technology used for this purpose. The performance of such electrolyzers is highly affected by various degradation processes occurring in such systems. In this project, we are aiming to understand the sources of […]

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Advancing the reliability of social media discourse as a measure of public sentiment about COVID-19

The proposed research is to develop a method for making valid, representative estimates of public opinion from sufficiently large and diverse non-probability samples such as social media data. We aim to demonstrate the theoretical, methodological, and practical contributions to the field of public opinion research by demonstrating the reliability and utility of this method in […]

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The art of working together: Community case studies supporting a model for collaborative arts informed research as social practice

The Art of Working Together: Developing a Sustainable Model for Arts Informed Research as Social Practice aims to strengthen the capacity of Centre[3] for Artistic and Social Practice (Centre[3]) to support community-based arts-informed research as social practice by developing a model for sustainable partnerships. Centre[3] has a long tradition of research collaborations with institutions (university/college/hospital), […]

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Accelerating Packaging Machinery Design and Assembly

Edson designs and manufactures innovative machines used for case packaging of goods, food, pharmaceuticals, and other products into corrugated boxes. Machine steps include automatic feeding of the boxes, folding, adding the product, and closing the box top. Market pressures require client ability to swiftly change over to package a new product. Edson must also be […]

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