During the past two decades, the CBOE Volatility Index (VIX® Index), a key measure of investor sentiment and 30-day future volatility expectations, has generated much investor attention because of its unique and powerful features. The introduction of VIX futures in 2004, VIX options in 2006, and other volatility-related trading instruments provided traders and investors access […]

The development of new strategies to improve drug delivery has the potential to significantly improve patient outcomes. Ripple Therapeutics has developed a new approach to developing implants based on a discovery that prodrugs (an inactive version of a drug) can be processed into an implant without the use of a polymer to hold the implant […]

Electrified vehicles (EV), which include hybrid, battery, plug-in, and fuel cell technologies, will be critical in helping lower emissions, reduce fossil fuel usage, and help mitigate climate change. The next generation of EVs will require significantly improved powertrains, components, and associated control technologies. The proposed project will research and develop components, architectures, and systems that […]

This project aims to develop a new technology for the production of biodegradable plastics that can decompose under various natural conditions, including soil and oceans, by up to 90%, which minimizes plastic waste and its environmental footprint. The technology will first target application in food packaging and drink containers, which is a main market for […]

There is no plant-based protein (PBP) that compares to whey protein isolate (WPI) on the growth and maintenance of muscle mass, as WPI contains all the building blocks of protein, known as amino acids (AA). The most important AA when it comes to muscle growth is leucine, which is not as high in PBPs. In […]

We are bringing together modern techniques in Bayesian machine learning to optimize process parameters for a state-of-the-art semiconductor fabrication process. The challenge is that while the process contains complex underlying dynamics and some degree of stochasticity, there are a large number of process parameters and a small number of samples to use for model training […]

The goal of the project is to develop, implement, and validate novel condition monitoring algorithms that can detect the onset of a failure through changes in behavior of the DC bus capacitors in motor drives with no additional sensors. This is an important research area as detecting the onset of a potential failure is of […]

The intent of this project is to reduce the cycle time in the vehicle repair process across the Carstar network. The project also includes developing process models that will help in guiding Carstar to reduce cycle time in major process steps for all stores of varying size and disparate locations. During the process of investigation […]

Iron-based nanoparticles can not only be used in sensitizers or absorbers but also retain excellent electrical conductivity, optical, electrical, and magnetic properties. So far, very few synthetic methods are known to implement stable Iron-based nanomaterials. We propose to develop novel synthesis routes to produce QDs. In addition, we plan to develop surface modification processes to […]

Nuclear power currently provides approximately 50% of Ontario’s electricity. Operation of nuclear power plants produces a variety of radioactive waste. In particular, low-level radioactive waste makes up about 95% of total non-fuel waste volumes. To reduce volume, low-level materials must be sorted to determine if their radioactivity has sufficiently decayed and they can be safely […]

The allergen inhalation challenge model is an important research technique for asthma drug development, and has been used for many years by the AllerGen CIC consortium of Canadian investigators in their evaluations of new asthma therapies. An alternate nebulizer is needed for performing inhaled allergen challenges, and this device needs to be tested for its […]

Individuals with post-traumatic stress disorder (PTSD) often struggle to relax, or simply be at ‘rest.’ In particular, recent research has revealed participants with PTSD show hyper-activity across the visual cortex while at rest. Referred to as sensory hyper-activity and disinhibition, altered resting-state patterns are thought to be underlying hypervigilance and re-living sensations clinically, as well […]