Rate-Distortion-Perception Theory

Unlike in lossless compression, the decoder in a lossy compression system has flexibility in how to reconstruct the source. Conventionally, some measure of distortion such as mean squared error is used as a quality measure. Accordingly, lossy compression algorithms are analyzed through rate-distortion theory, wherein the objective is to minimize the amount of distortion for […]

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Market Research and pricing project supporting the global roll out of a next generation drug screening platform

eye3 is a medical device development company based in Southwestern Ontario. Our research facilities are at McMaster University in Hamilton, with head offices in Port Credit. Eye3 is developing a next generation point of care screening device for detecting drugs of abuse. The platform utilizes a field friendly, ruggedized reader and cartridge system to test […]

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Smart Textiles for Health and Well-being

McMaster University is collaborating with National Research Council Canada (NRC) under the AiP program of NRC, to develop smart textile technology that will integrate energy components into textile wearable products to provide daily and on-demand physical stimulus to the aged wearers. It aims to slow down or prevent the development of age-related health problems. The […]

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Comparison of Pilot Scale and Industrial Trial Results for Advanced High Strength Steel (AHSS) Development.

Developing new high performance steels using pilot scale facilities such as those available at CanmetMATERIALS laboratory in Hamilton is more efficient and cost effective than using industrial lines. However, some recent projects carried out for Stelco Inc revealed unexpected discrepancies between pilot scale results and real industrial data. The aim of this project is to […]

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The Pan-Canadian Immunoglobulin Database: Enabling Utilization Reporting and Personalized Treatment Using Data Mining Techniques for Immunoglobulin

Immunoglobulin (Ig) is a blood product that is used for people who either lack IgG antibodies or require immunomodulatory therapy for life-threatening autoimmune conditions. The use of Ig products continues to increase each year, at an average rate of 8%. The COVID-19 pandemic has introduced additional stress on the Ig supply due to a reduction […]

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Clinical utility evaluation of a NGS based assay for the detection of genetic modifiers in families with reduced penetrance or uncertain copy number variants

There is increasing evidence that multiple genetic variants within a patient can compound their effects, resulting in a more severe clinical phenotype in comparison with the clinical manifestations in individuals with single genetic variation. In this study, we aim to examine the clinical utility of a massively parallel sequencing technique to identify clinically relevant secondary […]

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Restoring bacterial sensitivity to aminoglycosides antibiotics

Bacterial resistance to aminoglycoside antibiotics is a major public health problem. The WHO (World Health organization) has highlighted the urgent need to find new treatments to fight multidrug resistance MDR bacteria, as actual drugs are less effective or inactive. This research project aims to develop new chemical compounds to restore bacterial sensitivity to antibiotics currently […]

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Data Analytics Models for FreshBooks’ Customers’ Engagement

An organization that can effectively understand its specific customers’ needs will be able to follow the best communication approach and accurately measure engagements. A data-driven framework based on the customer’s digital behavior, historical data, will be developed to identify specific customer segmentation and used to find optimal next best action to enhance customer experience by […]

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Nonlinear photonics applications of tellurite-coated silicon nitride waveguides

This project is about integrated photonics. Similar to integrated electronics, both have many applications in our lives such as in communications, biosensing, security, display and imaging. Interestingly, photonic circuits are poised to replace electronics circuits in telecommunications and data centers. Compared to electronics, they will reduce cost, increase speed and bandwidth of the future Internet […]

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Fundamental Studies of Aerobic Membrane Bioreactor under Short Sludge Retention Time Conditions for Municipal wastewater treatment

Conventional wastewater treatment processes consume a large amount of energy and produce around 32% of municipal greenhouse (GHG) emissions. Thus, advanced wastewater treatment technologies with low energy consumption and GHG emissions are highly desirable for environmental protection. Aerobic membrane bioreactor (AeMBR) has been widely used for municipal and industrial wastewater purification. However, the AeMBR technology […]

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