A novel multi-echo MRI technique for prostate cancer detection and grading

We propose to develop a novel, clinically relevant MRI based technique for prostate cancer detection. We also propose to develop a novel reporting system that would be more accurate and easier to use by the radiologists. The new technique will be first developed on a research MRI scanner at UBC, and subsequently implemented on the […]

Read More
Characterization of adverse events, health-care costs and real-world survival outcomes with the introduction of ibrutinib for chronic lymphocytic leukemia/small lymphocytic lymphoma patients in British Columbia

Ibrutinib has proven to be very effective in newly diagnosed and relapsed chronic lymphocytic leukemia (CLL) patients. However, it can cause certain side effects that can lead to early discontinuation of treatment and worse outcomes for patients. The goal of this study is to determine the frequency of side effects in the “real-world” associated with […]

Read More
Is Obstructive Sleep Apnea a Novel Risk Factor for Cancer?

Obstructive Sleep Apnea (OSA) is an important disease characterized by recurrent blockages of the upper airway during sleep leading to breathing cessations (up to 100 times per hour); OSA is common and is widely under-diagnosed. OSA might cause cancer or lead to cancer progression, potentially mediated through low oxygen levels; however, evidence for this association […]

Read More
Endoscopic Laser Raman Spectroscopy for Colorectal Cancer Detection in IBD Patients

Inflammatory Bowel disease (IBD) affects over 200,000 Canadians. Individuals with IBD have significantly greater risk of developing colorectal cancer. Unfortunately, the screening for colorectal cancer that is currently provided to the general population is inadequate for this group. White light colonoscopy is currently the gold standard but is challenging, as lesions are sometimes difficult to […]

Read More
Governing innovation and knowledge sharing to increase adaptive capacity of forest industry in Quesnel, British Columbia

In Quesnel, British Columbia, efforts to stimulate innovation and diversify actors of local forest industry can be challenging for emerging locally-driven small forest enterprises that have limited capacity and resources. Building an inclusive forest industry that constitutes existing large forest enterprises and locally-controlled small forest enterprises in the landscapes therefore involves strengthening networks of knowledge […]

Read More
Targeting granzyme B with a novel inhibitor for the treatment of radiodermatitis

Radiodermatitis is a group of skin reactions that occur as a result of radiation therapy. It is a significant health challenge as approximately 70% of all cancer patients receive radiation therapy and approximately 95% of them experience radiodermatitis. Patients with radiodermatitis experience redness, itchiness, pain, scaling, and weeping or crusted wounds. Importantly, radiodermatitis can impede […]

Read More
Developing a machine learning-based diagnostic strategy to detect early onset of double negative prostate cancer by integrating SEMA3C-associated genomic variations and blood biopsies

The main goal of this research project is to study if a protein named SEMA3C can be a biomarker for early detection of an aggressive and lethal form of prostate cancer, named Double Negative Prostate Cancer (DNPC). To test if SEMA3C is a contributing factor in the progression of DNPC, we will compare SEMA3C level […]

Read More
Technology Innovations to Improve Patient Outcomes After Spinal Cord Injury

Spinal cord injury (SCI) results in severe paralysis, for which there are no effective treatments. Advanced technologies, however, can play an important role in assisting in the diagnosis, monitoring, and treatment of SCI patients who suffer many impairments beyond the loss of voluntary muscle control. In this proposal, we will develop and apply innovative technologies […]

Read More
Machine Learning Aided Self-Estimation of Device Position in Cellular IoT Networks

The research program in this project aims at advancing the use of cellular communications for Internet-of-Things applications. The academic researchers and the partner organization have identified three work items that revolve around the self-estimation of cellular IoT devices (1) to improve energy and spectrum efficient transmission of short and intermittent data packets, (2) to enable […]

Read More
Evaluation of value-added lignin-based bioproducts for commercial applications

During the production of pulp, in the pulp and paper manufacturing process, one component of the tree is extracted into the pulping liquid. This component, called lignin, has potential value as an important renewable material for adhesives, fibre, and coatings. The proposed research has the focus on evaluating the pulping liquid for all of its […]

Read More
Single-molecule analytics of RNA/DNA drug constructs interacting with RNA targets and with lipid nanoparticle delivery vehicles

In this project, the interns will develop a new set of tools and techniques to provide new scientific insights into the detailed interactions that occur between drug and target molecules in the human body. Understanding of these interactions is critical to design better, more effective, and more precisely targeted drugs. The problem is that current […]

Read More