Blood flow within microfluidic conduits

A current area of focus at SMT Americas is to develop injection-moulding methods for medical lab-on-chip (LOC) devices, particularly to transport and process blood and plasma while eliminating conduits clogging and reducing sample loss. This project will evaluate the effect of flow conditions on viscosity of samples, and the adequacy of conduit structures achieved with […]

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Validation of Selective Phytocannabinoids Using In Vitro Glaucoma Models

Glaucoma is the second leading cause of blindness in the world, mainly induced by increased pressure in the eye. Marijuana has been shown to reduce such pressure, thus benefit glaucoma patients. In the previous project, we screened several individual components from marijuana extracts and tested their ability on keeping cells alive. The current project puts […]

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Molecular signatures and predictive biomarkers for phenotyping allergic rhinitis responses

Allergic rhinitis (AR) is in inflammatory disease characterized by nasal symptoms. It affects 20-25% of Canadians and is recognized as the most common allergic disorder worldwide. Patients can experience one of several types of responses to allergen onset hence a key hurdle to developing effective treatment plans is accurate diagnosis. The allergic responses are characterized […]

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Towards a Theory of Blockchain as a Socio-Informational-Technical System

Blockchains operate as perhaps the most promising system of trust for any type of digital transaction of value — everything from cryptocurrencies to patient medical records. But a number of barriers — involving social institutions, data and identity management and technological processes — stand in the way of broader adoption. These challenges also ultimately speak […]

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Toward an understanding of how YB-1 regulates drug resistance in glioblastoma multiforme through epigenetic regulation governed by BMI-1.

Glioblastoma (GBM) is the most common and aggressive form of brain cancers and is the second most common cancer in children only behind leukemia. Conventional therapy consists primarily of surgery, radiation, and chemotherapy, and while these approaches have slightly improved the length of patient survival, there remains no cure for this disease. With the emerging […]

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Evaluation of biological-based source control methods for preventing constituent release from mine wastes

Mine waste rock drainage is one of the most challenging and lasting global environmental issues facing the entire mining industry, regulatory agencies and society as a whole. Mine drainage can be alkaline, neutral, moderately or extremely acidic and contains significant levels of sulfate, dissolved iron, and frequently a variety of heavy metals and metalloids. As […]

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Assessing the Efficacy of Empathetic Computing

As the digital landscape continues to evolve, it becomes increasingly more important to understand how technology affects cognition, emotion, and behaviour. This rapid growth of technology has also led to the development of empathetic computing programs with the goal of augmenting people’s lives. It is crucial to discover the practical implications of these systems. This […]

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Masters Athlete Screening Study (MASS) – Part 2 (5-year evaluation)

Masters athletes (>35 years) are a rapidly growing population that participate in a variety of sports. While exercise has tremendous health benefits, there is a small absolute risk of a heart attack and sudden death during exercise. Prevention strategies, such as heart screening aim to identify heart disease that may serve as a trigger for […]

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Automated malware detection using supervised machine learning

Malware is one of today’s biggest computer security problems. Traditionally, malware is detected by inspecting its signature, which is a unique identifier of the software’s binary. Signature-based malware detection is becoming less effective as cyber criminals mutate the malware they design, where the malware is programed in such a way that simply comparing its signature […]

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