Formulation and Toxicology of Bone-Targeting Nanoparticles

Bones undergo a renewal process by replenishing calcium mineral through a cellular process known as remodeling. Usually, it happens in a balanced manner, but in many bone diseases, the remodeling process is increased with regional bone metabolism. Bisphosphonate (BP) drugs selectivity and strongly bind to bone mineral and become incorporated at active sites of bone […]

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Formulation and Toxicology of Bone-Targeting Nanoparticles – Year two

Bones undergo a renewal process by replenishing calcium mineral through a cellular process known as remodeling. Usually, it happens in a balanced manner, but in many bone diseases, the remodeling process is increased with regional bone metabolism. Bisphosphonate (BP) drugs selectivity and strongly bind to bone mineral and become incorporated at active sites of bone […]

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Performance evaluation of a Novel “Displacement Buffering System” for Buried Pipelines

ALFA Upgrades recently developed a system for buried pipelines, referred to as “Displacement Buffering System (DBS)”, to redistribute the stress and strain concentrations in a pipe and limit the allowable lateral displacement of the pipe in the incidence of large ground movement. The scope of this project includes performing experimental tests and consequently developing equations […]

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Pre-clinical development of a novel antioxidant

Both ?-lipoic acid (ALPHA-LA) and Acetyl-L-carnitine (ALC) are used to control many diseases due to their antioxidant . We have evidence indicating if the two compounds are chemically attached, superior pharmaceutical properties are achieved. These evidence have resulted in a patent that gives the sponsoring Company exclusivity on its use. The proposed project is developed […]

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Mathematical modelling and numerical simulation for efficient sprinkler system

InteliRain Inc. has developed an effective sprinkler system producing excellent uniformity water distribution for regular or irregular areas but using 30% less water compared to most existing standard industry system. However, the performance of the InteliRain system deteriorates rapidly when it is tested in an open field with wind effect. In this project, the intern […]

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Scoping Review- Aboriginal Women, Domestic Violence, and Homelessness

Several studies have documented the high risk of housing instability and homelessness for women as a result of domestic violence and the broader issue of violence against women. Aboriginal women have been identified as being more vulnerable due to unique barriers to achieving housing stability, including racism and the lack of culturally appropriate services. This […]

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Large-Scale Purification of Antifungal Oxylipids via High-Speed Counter Current Chromatography (HSCCC) and Their Identification Using Liquid Chromatography–Mass Spectrometry (LC-MS)

Phyto-pathogenic fungi are one of the main concerns threatening agriculture in Canada. Those phyto-pathogens not only affect the yield and the quality of agricultural products, but their metabolite, represented by mycotoxins, will also endanger food safety. In the pursuit of innovative environmental-friendly fungicides, oxylipid is of great research-importance because oxylipid with specific structures can act […]

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Investigation of Pore-scale Mechanisms of Applying CO2 Huff-and-Puff to Enhance Shale Gas Recovery with Nuclear Magnetic Resonance

Considering the unique properties of CO2 under supercritical condition, CO2 is proposed to be used in huff-and-puff treatments to enhance shale gas recovery from shale gas formations. This research project will look at the fundamental pore-scale mechanisms when CO2 huff-and-puff is used for enhancing methane recovery from shale formations. In order to obtain pore-scale mechanisms […]

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Application of spent hen adhesive for engineered wood products

In the egg industry, as the hens are at the end of their productive lives they are of little economic value to the farmers and seen as a by-product or a waste which require disposal. Disposal of spent hens is a long-existing liability to the egg industry for paying associated cost of handling, transportation and […]

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