Investigating strategies for optimizing immunity to COVID-19: examining the impact of probiotic lactic acid bacteria-derived secretomes on epithelial cell and macrophage immune activity

Strategies to promote immune defences against COVID-19 infection are urgently needed. The gastrointestinal tract is a potentially important route for COVID-19 infection and for generating protective anti-viral immunity against this pathogen. Certain features of COVID-19 contribute to its ability to evade and subvert our immune defences. Type I interferon is a key immune protein that […]

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Safe and Low-cost Robot Grasping through Impedance Control and Deep Learning

Grasping skill is significant in modern service robot that requires interaction with object under manipulation. Grasping of a new object is a trivial task for human operator while it is challenging for robot manipulators. Inspired by the grasping process of human operators, grasping control algorithms based on the integration of vision, tactile sensing. Deep learning, […]

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Probiotic lactic acid bacteria-derived secretome impact on intestinal epithelial and antigen-presenting cells: determining effects on immunometabolic and epigenetic reprogramming in the context of cell interactions

While intestinal bacteria are increasingly understood to be important for maintaining health, many questions remain about how probiotic bacteria act to influence the immune system. We have previously found that one of these bacteria, Lactobacillus rhamnosus R0011, produces mediators able to influence communication between intestinal epithelial cells and antigen-presenting cells, cell types important for our […]

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Pneumatic Based Clean Powering Options for Buses

This project aims to develop a pneumatic (compressed air) powertrain to be used in a 40-feet bus for municipal transit and school buses. Since the transportation sector is one of the prior contributors of Canada?s GHG emissions ( 24%), any alternative solutions to conventional vehicles carries significant importance to reach the GHG target that Canada […]

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