Prototype Behavior Based Integrity Verification (BBIV)

Web computing, in which the world-wide web is itself employed as a distributed computing platform, is entering a stage of rapid expansion with the advent of Open Web Platform so that programs that once worked only a native environment on desktop, tablets or phones can now work from within a browser itself. There is therefore […]

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Development and characterization of elite Echinacea germplasm for natural health products and dietary supplements

Echinacea is a popular medicinal herb with a global market of ?$1 billion. While numerous Echinacea products are already available, variable plant chemistry and genetics leads to inconsistent product quality. In an effort to develop “chemically customized” varieties for herbal products and supplements, Amway Canada has partnered with researchers at the University of Ottawa and […]

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Effects of dietary glutathione precursors on cellular redox and mitochondrial efficiency in adults consuming a defined hypocaloric diet (Optifast-900; Nestlé Canada)

The aim of the proposed research is to investigate the cellular mechanistic effects of supplementation with a hypocaloric meal replacement product (Optifast-900; Nestlé Canada) containing cysteine and glycine, which are amino acid precursors of the antioxidant glutathione. Impaired cellular glutathione redox normally occurs with aging and metabolic disorders, however, this study will focus on a […]

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Effects of dietary glutathione precursors on cellular redox and mitochondrial efficiency in adults consuming a defined hypocaloric diet (Optifast-900; Nestlé Canada) – Year two

The aim of this research is to investigate the cellular mechanistic effects of supplementation with a hypocaloric meal replacement product (Optifast-900; Nestlé Canada) containing cysteine and glycine, which are amino acid precursors of the antioxidant glutathione. Impaired cellular glutathione redox is evident in obesity and metabolic disorders; Therefore, this study focuses on a population in […]

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Biomechanical Evaluation of the Endolite LiNX Prosthesis

The LiNX prosthetic system combines microprocessors, sensors, and actuators for simultaneous control of the prosthetic foot and knee. Bi-directional electronic communication coordinates responses to variations in terrain and speed, adjusting for a transfemoral amputee’s situational needs. This study will use state-of-the-art virtual reality technology (CAREN-Extended system) to compare how people with transfemoral amputations walk with […]

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Design and Implementation of a Framework for Performance Management in Service Oriented Virtual Organizations (SOVO PM)

In this research, we propose a framework for performance management in virtual organizations (VOs) equipped with service oriented architecture (SOA). This framework enables networks of organizations to evaluate and manage their collaboration performance and also to align and coordinate their various goals and objectives. Distributed management of VO will be enhanced to reduce the necessity […]

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Harnessing epigenetics to improve muscle stem cells function in degenerating myopathies

Duchenne Muscular Dystrophy (DMD) is an incurable progressive myopathy, caused by the absence of the dystrophin protein. It is characterized by permanent myofiber necrosis, leading to continuous activation of muscle stem cells (MuSCs), that eventually cannot support muscle repair leading to replacement of the muscle by fibro/fatty tissue. We have observed that epigenetic changes in […]

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