The ever-growing demand for energy storage, especially with high density and low-cost, has both academia and industry research communities working hard to develop and optimize energy storage technologies. Among the top energy storage technologies are Lithium metal batteries (LMBs) which have an exceptionally high specific capacity (3860 mA h g?1) in comparison to that of […]

Solid-state nanopores—small holes in thin membranes comparable in size to individual molecules—are promising candidates as sensors with which to revolutionize DNA sequencing, personalized medicine, point-of-care diagnostics, and next-generation information storage methods. A method by which these nanopores can be fabricated on an industrial scale was recently invented, but challenges remain, particularly in quality-controlling source materials […]

Future Ancestors Services seeks to build a database that explores the teachings of various peoples around the world and what ancestry and ancestral accountability means to them in the context of current socio-political and environmental issues. This research project explores the ways in which the lived experiences of black people in Sub-Saharan Africa impact their […]

In Finance, the use of Automated Trading Systems (ATS) on markets is growing every year and the trades generated by an algorithm now account for the majority of orders that arrive at stock exchanges. Historically, these systems were based on advanced statistical methods and signal processing able to extract trading signals from financial data. However, […]

Energy-efficiency upgrades of existing buildings offer substantial energy and greenhouse gas emission reductions. Infrared thermography (IRT) of the building envelope is a non-destructive test that can be used to target retrofit actions and motivate energy efficiency improvements. Recent advances in IRT technology include using drones to collect thermal imaging data from the buildings efficiently, thoroughly, […]

In this project, an oncolytic virus will be generated that combines the safety profile of vaccinia virus, with the immunostimulatory power of RNA-vaccines. Currently, the RNA-genomes of Alphaviruses are successfully used to encode proteins to be vaccinated against. Their special genome organization and makeup allow them to self-amplify within a cell. This replication in turn […]

One rapidly evolving area of cancer therapeutics is immunotherapy, which aims to drive a cancer-targeted immune response in tumors. Replicating virus-based therapeutics are a novel cutting-edge immunotherapy that have shown promise clinically. Turnstone Biologics has developed a novel cancer-killing virus with the capacity to deliver multiple payloads to further enhance the virus’ anti-cancer effects in […]

Oncolytic viruses (OVs) are promising biotherapeutics that selectively infect and kill cancer cells. The efficacy of oncolytic viral therapy depends on the virus’s efficient replication and dissemination within tumors. However, tumors often develop a dense extracellular matrix (ECM) surrounding their cells that provides resistance against many forms of cancer therapies including OVs. To overcome this […]

Through engineering and selection strategies, we have created novel cancer-killing oncolytic viruses (OVs) that are selective for tumours but are unable to grow in normal tissues. A critical component of the therapeutic activity of this class of therapeutics is the induction of an anti-tumour immune response, which can be suppressed in many tumours. One strategy […]

Refrigerants have a wide range of applications in Canada, from their support for the food industry (storage and transport) to their key role in recreational sports like hockey, curling and ice-skating. Although current hydrofluorocarbon refrigerants have solved previous problems associated with depletion of the earth’s ozone layer, they still suffer from high global warming potentials. […]

This proposal aims to develop the next generation of smart materials to remove hazardous substances Canadians breathe in different environments from enclosed public buildings to industrial facilities. These hazards put the Canadians at risk, especially when in chronic contact even at low concentrations in the air. The Canadian company HFI Pyrotechnics Inc. and the University […]

Health services delivered over the internet, often referred to as telehealth services, are becoming an increasingly important way of providing healthcare. This has been highlighted by the COVID-19 pandemic and the necessary shift to online service delivery for many organizations that followed. Although there is some evidence that telehealth delivered mental health services are as […]