This project will be focused on implementation of an algorithmic model to help us better understand the underlying processes of recognition memory. Specifically, our computational model is comprised of two memory modules – one representing the hippocampus and the other representing the perirhinal cortex of the brain. According to the dual-process model of recognition memory, […]

Desiccation-induced cracking is a complicated phenomenon associated with strongly coupled hydro-mechanical behavior of cohesive soils. The soil-shrinkage characteristic curve (SSCC) for intact soils is well established to describe the relationship between void ratio and water content. However, it is questionable to employ the SSCC to predict the volume change based on the reduction in water […]

Osteoarthritis is an extremely common, extremely costly disease that will become more prevalent as the population ages. Treatment delivered in primary care settings does not always reflect ‘best practice’ care for the disease. In particular, non-surgical and non-drug interventions such as exercise, weight loss and education regarding self management are underutilized. One reason that clinicians […]

The Élisabeth Bruyère Research Institute is interested in addressing an organizational challenge associated with its size and the geographical location of its partners, which form a research community that is spread over multiple sites located in distant parts of the city. The large number of researchers and physical disconnection of the buildings limit social interaction […]

Regulations are introduced to ensure the well-being, safety, and other societal needs of citizens and organizations. Yet, regulators often have difficulties assessing the performance of their regulations, and whether regulatory initiatives actually improve compliance. This project’s main objective is to investigate the suitability of a framework combining a standardized goal modeling notation with an existing […]

The intern will be producing a therapeutic protein, i.e. ‘biologic’ (BMP2) using mutated bacterial plasmids as the bio-factory. The intern will create a sequence of DNA to be transformed into E. coli cells (BL21). The cells will be grown up in the lab, and studied for enhanced clinical efficacy. Proteins will be affinity purified and […]

As Canada’s infrastructure grow older every year, the inspection and maintenance of these capital intensive assets becomes more challenging. Most deterioration mechanism occur over a long period of time. Certain defects remain unnoticed during regular inspection until it is too late. Unfortunately, delayed diagnosis of defects can significantly increase the annual cost of maintenance. Inspectors […]

Cold Spray is an established coating additive manufacturing process. Centerline has the opportunity to establish itself in a very large worldwide market if they can improve the ability of their cold spray process to metallize polyamide 6-6 substrates with enhanced deposition efficiency. The overall general objectives are twofold: 1) Analyze experimentally the cold spray process […]

Disorders, such as diabetes and Alzheimer’s, have metabolic profiles that are detrimentally affected by the course of the disease. Both diet and exercise have demonstrated an ability to slow the progression of neurodegenerative illnesses and their symptoms. We hypothesize that this benefit is a direct result of an increase in the brains ability to efficiently […]

Continuous blood pressure (BP) monitor is highly beneficial for detection and prevention of stroke and cardiovascular disease. The most common BP monitor technique still relies on using a cuff that slows the blood flow, which is both uncomfortable and makes continuous monitoring impossible. Furthermore, research has shown that due to the numerous artifacts, the existing […]

The project aims to validate the effectiveness of “phase contrast” synchrotron (x-ray) imaging techniques in detecting very small-scale features (particularly amyloid plaques) commonly associated with the onset of Alzheimer’s disease. This will be done though comparison of synchrotron-generated images of Alzheimer-afflicted brain tissue, against their optical microscopy image counterparts. The experimental process will involve five […]

The great interest of shifting towards biodiesel from vegetable oils or was fats is leading to a tremendous increase of glycerol production as an inevitable by-product. This waste sparked the need for glycerol valorization to justify biodiesel as alternative for diesel from petroleum. Our research efforts are to partially electro-oxidize glycerol into value-added chemicals in […]