Pharmacogenetic Biomarker Discovery, Personalized Medicine, and Clinical Test Commercialization in Neuropsychiatry – Year two

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral fellow project involves the use of pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of pharmacogenetic testing. A main component of […]

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Development of Fungal-Specific Stress Response Inhibitors for the Treatment of Fungal Infections

Drug resistance of medically relevant microorganisms poses a grave threat to human health and has severe economic consequences. Fungal pathogens pose an additional complication as they are closely related to their human host. Current therapies to treat fungal infections are limited and drug resistance has already emerged in the clinic. We have conducted extensive research […]

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Ontario Primary and Mental Health Policy Decision Tool

The Ontario government provides healthcare funding to fourteen Local Health Integration Networks (LHINs) across Ontario. LHINs in turn are responsible for structuring health care delivery and allocating funds to best meet the needs of the population in the region. However, there are limited tools available to help LHINs evaluate the system-wide implications of proposed policy […]

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Multi-Perspective Text Analysis of Social Knowledge Networks

Knowledge workers (i.e., researchers, business consultants and analysts, research-program managers) produce documents (research publications, analysis reports, opinion pieces, calls-for-proposals, and blog posts) through which they express their knowledge and opinions. They also read and review similar documents, produced by individuals and organizations in their domain of interest and expertise, to keep current with their domain. […]

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Evaluating the possibilities for a new generation light source for infrared spectroscopy and spectromicroscopy

Infrared spectroscopy is a fundamental technique to study novel materials ranging from medicine to semiconductor industry. Regular infrared sources can provide very limited spatial resolution for infrared microscopy experiments. Currently, this limitation can be overcome with the use of synchrotron sources. A recently discovered and now commercially available alternative light source is the Quantum Cascade […]

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