Many genetic diseases caused by small genetic mutations do not result in complete loss of protein fnction, but rather are due to the degradation of mutant protein by a “quality control” mechanism (endoplasmic reticulum-associated degradation-ERAD) soon after it is made. Prominent amongst such ERAD-dependent diseases is Cystic Fibrosis(CF), a chronic, progressive, life-threatening genetic disease that […]

Polyurethane foams are so commonly used, from rigid dashboards in cars, to insulation in buildings, and the comfy mattresses we sleep upon. Replacing the petrochemical resources used to make them with renewable resources like bark would be a great stride towards sustainability. In order for this to be done the conversion process of bark into […]

The proposed research project investigates two transnational teacher communities between Ontario and Shanghai secondary schools. Teachers’ cross-cultural professional learning is the focus of the study. To understand how, why, and what teachers learn from each other, the project needs to collect data from both countries. While in China, data collection will be completed in two […]

Unprecedented advances have been made in Radiation Therapy during the past two decades. High precision treatment plan is generated using sophisticated optimization methods, and treatment is delivered with complex intensity modulation techniques. Due to the complexity, the burden of Quality Assurance (QA) for modern radiotherapy has also increased dramatically. Many staff and machine hours are […]

Research findings demonstrate that comprehensive sexual health education (CSHE) can reduce negative health outcomes and increase positive health outcomes. In order to be effective, CSHE must address the unique cultural, geographic, and social needs of youth. There are currently no studies that explore youth or educator sexual health education needs within the Yukon territory. SIECCAN […]

This project aims to create and deliver an online curriculum which will teach clinicians about the Women-Centred HIV Care (WCHC) Model while help ensure clinicians provide more equitable, trauma-informed, gender-responsive, person-centred care to women and gender-diverse people living with HIV. Women and gender-diverse people living with HIV often face barriers such as stigma, discrimination, or […]

The project is focused on study of commercial microbial cultures for biological remediation of soils and ground waters contaminated by chlorinated organic compounds. The successful elaboration and improvement of the products requires analysis on molecular-genetic level and detailed understating of organization of the microbial communities. The work benefits to industry partner by providing comprehensive information […]

Picton Mahoney Asset Management (“PICTON Investments”) was founded in 2004 to provide unique investment solutions to institutional, retail, and high-net-worth investors in Canada and globally. The Quantitative Research and Risk team at PICTON Investments is dedicated to developing and maintaining models that support investment decisions and risk assessments. With the increasing complexity of financial markets […]

Recent years have witnessed a boom in the construction of modern high-rise buildings in megacities around the world. It is important to design a high-rise building that can effectively withstand both wind and earthquake loads. Nonetheless, in current practice, the design of high-rise buildings for wind and earthquakes is done independently. Hence, there is an […]

Cortland Credit is a rapidly growing alternative investment manager specializing in private debt and public bond portfolios. Five years ago, the firm operated with fewer than 15 employees; today, the team has expanded to over 30 professionals. With this growth, the firm’s existing data management system – based primarily on Excel and CSV files stored […]

To improve how diseases are treated, our team has developed a single, versatile platform that supports rapid drug discovery, therapeutic safety testing, and evaluation of cell-based therapies. In the longer term, the same technology will enable the bioengineering of transplantable human organs. Our initial work targets the kidney, pancreas, and lung—organs central to major chronic […]

Picton Mahoney Asset Management (PICTON Investments) was founded in 2004 to provide unique investment solutions to institutional, retail and high net worth investors in Canada and around the world. They are 100% employee-owned and manage approximately $15.3 billion in sub-advisory, pension plan and hedge fund assets on behalf of their clients. The Multi-Strategy Team at […]