Un analyseur d’images automatisé de dimension n pour classifier les lésions et les tissus cérébraux chez les patients à partir d’images RM

NeuroRx est une entreprise basée à Montréal (Québec), qui propose une gestion professionnelle des activités liées à l'étude des IRMs et livre des mesures précises des résultats d'IRM, en conformité avec une réglementation donnée. Le projet du stagiaire prévoit d'examiner les problèmes informatiques associés à l'analyse multidimensionnelle, c'est-à-dire l'efficacité computationnelle et l'utilisation de la mémoire […]

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Calcul précis de l’atrophie du cerveau due à des lésions focales chez les patients atteints de sclérose en plaques : modification d’un algorithme d’enregistrement non linéaire

NeuroRx est une entreprise basée à Montréal, Québec, qui propose une gestion professionnelle des activités liées à l'étude des IRM et livre des mesures précises des résultats d'IRM, en conformité avec une réglementation donnée. Le projet de recherche du stage fera appel au traitement d'images pour quantifier les changements de volume locaux, basés sur les […]

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MRI Estimates of Repeated Demyelination and Tissue Injury as Markers of Progressive Multiple Sclerosis

Multiple Sclerosis (MS) can be divided into three clinical phenotypes: relapsing remitting (RRMS), secondary progressive (SPMS) and primary progressive (PPMS). RRMS is characterized by episodic worsening followed by full or partial recovery, whereas SPMS and PPMS are characterized by steady accrual of disability.Progressive MS remains poorly understood and generally fails to respond to therapies that […]

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Precise Calculation of Brain Atrophy Due to Focal Lesions in MS Patients: Modification of Non-linear Registration Algorithm

NeuroRx is a Montreal, QC-based company which provides professional management of MRI-related study activities and delivers precise MRI outcome measurements that are performed in a regulatory compliant environment. This internship research project will involve image processing to quantify local volume changes in serial MR images of the brain based on deformation field analysis using techniques […]

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An Automated N-Dimensional Brain Tissue and Lesion Classifier in MS Patients using MR Images

NeuroRx is a Montreal, QC-based company which provides professional management of MRI-related study activities and delivers precise MRI outcome measurements that are performed in a regulatory compliant environment. The intern’s project will involve examining the computational issues associated with multi-dimensional analysis, namely, the computational efficiency and memory utilization, while creating an N-dimensional algorithm for segmenting […]

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QU02 MRI: a new window on mitochondrial dysfunction in Alzheimer’s disease

This project seeks to develop new methods for imaging oxidative and vascular function in the brain. The methods under development are based on widely available MRI hardware, which will make them feasible for use in future clinical drug trials, an application that is of interest to the partner organization CQDM. Before the approach is ready […]

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Using multivariate deep-learning algorithms for automatic quality control of high-resolution MRI

NeuroRx is an imaging contract research organization (CRO) specialized in the central nervous system (CNS) that utilizes state-of-the-art digital image processing techniques to produce accurate and precise outcome measures for clinical trials of drugs in development. Prior to analysis, all scans must pass Quality Control (QC). The goal of this project will be to incorporate […]

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Using multivariate deep-learning algorithms for automatic quality control of high-resolution MRI – Year two

NeuroRx is an imaging contract research organization (CRO) specialized in the central nervous system (CNS) that utilizes state-of-the-art digital image processing techniques to produce accurate and precise outcome measures for clinical trials of drugs in development. Prior to analysis, all scans must pass Quality Control (QC). The goal of this project will be to incorporate […]

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Specific Evaluation of Lesion Categories

Multiple Sclerosis (MS) is a debilitating disease that primarily affects young individuals. Disease Modifying Therapies (DMT) developed in the past two decades have greatly improved the quality of life for people living with MS. Assessment of brain lesions using Magnetic Resonance Imaging (MRI) has been a standard method to evaluate the efficacy of DMT in […]

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Evaluation of MRI-based estimation of cortical thickness

The most important structure in the human brain is the cerebral cortex. It makes it possible to perceive our visual environment and sounds, to perform motoric actions such as grasping an object, to speak, to understand speech, etc. The cerebral cortex is a 2-5 mm thick sheet, embedded in the skull. Analysis of MRI data […]

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