Interaction of Cyclin-dependent kinase 2 with CR6-interacting factor 1, and the inhibitor search for such interaction against leukemia treatment resistance

Cyclin-dependent kinase-2 (CDK2) regulates cell cycle, whose structure and biological characteristics are well known. CRIF1 plays a regulatory role in the bone marrow microenvironment-induced leukemia cell cycle arrest through inhibiting CDK2. In this multi-disciplinary research, we will use a combined structure function study to reveal the interaction between CDK2 and CRIF1. This will facilitate the […]

Read More
Sentiment Analysis with Parsed Representation of News Articles

Information published by financial news agencies is used as one of the inputs to make investment decisions. News articles from multiple sources can be used to gauge market sentiment towards an industry or a specific company. Deep learning techniques have been successful in producing state of the art results on various benchmark datasets (Dai & […]

Read More
Mapping issues and stakeholders related to the development of Canada’s restoration plan for the Great Lakes and St. Lawrence Basin

The Great Lakes St Lawrence (GLSL) Basin is central to Canada’s economy and culture, and a primary water source. Several stressors are deteriorating these critical ecosystems. This proposed project aims to lay the foundations for efforts to improve coordination related to the restoration of the GLSL region. The proposed project consists of mapping stakeholders, issues, […]

Read More
Investment portfolio design and optimal execution of automated trading strategies: An exploratory research program

Non-parametric models such as supervised and unsupervised machine learning algorithms seem to be an interesting choice when trying to extract decision-making signals out of this ever-increasing volume of information. These models have been used extensively in the last decades and are now more relevant than ever thanks to the development of new techniques in artificial […]

Read More
Ignition control on DME/OME engines

Considering the soot-free burning characteristics of DME/OME fuel, highly diluted intake charge can be introduced in order to realize ultra-low nitrogen oxides emissions. However, the ignition process of the highly diluted fuel/air mixture is difficult, and an unstable ignition process is detrimental to fuel efficiency and engine performance. In this project, innovative ignition systems including […]

Read More
Les indicateurs de performance de l’Industrie 4.0 : une étude empirique auprès d’entreprises manufacturières québécoises

Lorsqu’une entreprise investit de larges sommes d’argent dans une technologie, elle espère en tirer des bénéfices : diminution de ses coûts d’opérations, amélioration de la relation client, amélioration de la qualité des produits, etc. Ces faits sont mesurés à l’aide d’indicateurs de performance. Chaque entreprise est libre de choisir les indicateurs qu’elle souhaite suivre, mais […]

Read More
Habitudes d’utilisation de thermostats à tension de secteur

Les thermostats à tension de secteur pilotent le plus grand poste de consommation énergétique des résidences chauffées par plinthes électriques. Jusqu’à maintenant, les habitudes d’utilisation de ces thermostats par les occupants des résidences étaient obtenues par sondage, ce qui limite la quantité et la qualité de l’information récoltée. Le stage vise à traiter les données […]

Read More
A decision support framework for optimizing tube utilization in laboratory tests

In this project, the intern will design a decision support framework for optimizing tube utilization in laboratory tests. Given a prescription, the framework automates the tube selection process and outputs low cost tube configurations. The framework is designed to be easily adapted to different lab configurations. It consists of three processes, namely data profile configuration, […]

Read More
Resource potential of the Post Creek Property, Sudbury, Ontario

Sudbury represents the site of a meteorite impact structure originally greater than 200 km in diameter and that formed 1.85 billion years ago. Despite the proven and potential economic benefits of resource development at Sudbury, there are still major outstanding questions concerning our understanding of the structure and its ore deposits. A series of objectives […]

Read More
Applied Machine Learning for Malware and Network Intrusion Detection

Wedge Networks is a leading cybersecurity solution provider in Canada. In this project, we aim to investigate the application of statistical machine learning and deep learning to cyber threat detection, aiming to detect both network intrusions and malware binaries transmitted in the network. Based on the big data collected from Wedge’s system logs and anonymized […]

Read More
Prediction Improvement on User’s Consumption

The goal of the research is to implement different data mining algorithms in order to improve the prediction on a user’s electricity consumption. The research will be dedicated to improve the existing algorithms or implementing new algorithms for the improvement of the prediction accuracy. Besides application of the prediction algorithms, different data pre-processing methods will […]

Read More
Development and Demonstration Engine Technology for Class 8 Heavy Duty Trucks Fueled by Waste Hydrogen

Hydra Energy Corporation Commercial Demonstration Project will be based in Prince George, British Columbia 12.4 MT/day of waste hydrogen will be captured, purified and transported to an onsite hydrogen refueling station from which (at least) 53 Class 8 tractor-trailer trucks will refuel daily. Hydra’s demonstration project can provide a significant reduction in fleet greenhouse gas(GHG) […]

Read More