Analysis of TGF-? traps as effective immunostimulating cancer treatments

AVID200 is a TGF-? trap that specifically sequesters TGF-?I and TGF-?III to enhance antitumour immunity to inhibit tumor growth. AVID200 also avoids adverse side effect of depleted of TGF-?II. AVID200 is relatively short-lived in circulation, decreasing its capacity to exert desirable enhancement of anti-tumour immunity. To increase the effectiveness of TGF-? traps, a panel of […]

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Évaluation préliminaire des scénarios de restauration du parc principal à résidus minier de la mine LaRonde

Une grande partie des rejets produits par l’industrie minière est souvent entreposée en surface. En contact avec l’oxygène atmosphérique et l’eau, les minéraux sulfureux contenus dans ces rejets s’oxydent et génèrent un drainage minier acide (DMA) comportant des contaminants préjudiciables pour l’environnement. Une des techniques utilisées pour contrôler ce phénomène est les recouvrements à plusieurs […]

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Interactive preference elicitation application for book recommendations

Kobo is an online e-book retailer that provides recommendations for future purchases to its user base. One difficulty that recommendation systems face is what is known as the “cold-user” problem. In this scenario, when we know so little of a user’s preferences (for example, if they are new to the platform), we do not have […]

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Advanced Manufacturing of Graphene Oxide Membranes for Acoustic Drivers

The Graphene Audio group at TandemLaunch is working to revolutionize loudspeaker design through the use of graphene composite materials (Graphene-CMs) in loudspeaker membranes. Graphene is a newly discovered material with exceptional mechanical and electrical characteristics. Its low mass and high strength make it ideal for use in acoustic transducers offering an immediate benefit over existing […]

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Neurophysiological risk factors in Adolescent Sexual Offending

Sexual offending is a major public health concern in our society, with 21% of those charged with sexual offenses being adolescents between 12 and 19 years. Characteristics of these youth include antisocial attitudes, and problems with self-regulation and intimacy, problems that interfere with learning, social maturation, and appreciating the rights of others. To date, theories […]

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Investigating Distributed Ledgers for IoT and Connected Vehicles

With the fast-moving pace of the auto industry moving to more and more computing units, connected infotainment, pairing of on-board equipment to mobile devices, cloud connectivity, V2V, V2X, and autonomous functions, architects and developers need all the help they can get to address security and safety concerns in the systems. This internship will look at […]

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Contrôle de l’incertitude par une approche géostatistique en temps réel des sites contaminés

La réhabilitation des sites contaminés est l’un des défis stratégiques en vue d’une urbanisation durable. Toutefois, plusieurs obstacles freinent leur réaménagement, tout particulièrement l’incertitude liée à leur réhabilitation. Bien que le contrôle de cette incertitude représente un facteur clé facilitant le réaménagement des sites contaminés, il est pourtant peu étudié et maîtrisé, voire inexistant dans […]

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Fostering Corporate Productivity through Creativity and Intuition

Research shows that many business employees are disengaged with their work, leading to numerous negative outcomes such as reduced productivity and burnout. The use of creativity and intuition have been suggested as two potential avenues for resolving these issues. However, there is a lack of direction for how these concepts can be practically applied in […]

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Expérimentation et évaluation d’un dispositif de récolte des laminaires de culture et élaboration d’un programme de travail intégré sur la mécanisation de l’algoculture.

De nos jours, les algues de cultures attirent de plus en plus l’intérêt des consommateurs et des industries québécoises. En effet, elles regorgent d’éléments nutritifs et comportent des propriétés intéressantes tant pour l’alimentation que pour l’industrie pharmaceutique. Cependant, les pêcheurs québécois font face à plusieurs défis techniques et économiques pour répondre à une demande croissante. […]

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SSI efficacy in treating infectious colitis

Inflammatory bowel disease (IBD) is a disease with unknown etiology that is characterized by uncontrolled intestinal inflammation and microbial dysbiosis. Qu Biologics’ Site Specific Immunomodulators (SSI) are a platform technology shown to improve the status of people living with IBD (Crohn’s disease and ulcerative colitis), with most of those patients showing clinical improvement also going […]

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