The Sorensen laboratory-based Childhood Cancer Research Program is specifically focused on elucidating the genetic and biological determinants of the metastatic process in childhood cancer. Metastatic disease remains the single most dominant driver of adverse outcome in most childhood cancers, particularly in childhood sarcomas. Cancer stem cells, malignant cells that share many characteristics with normal stem […]

Emerging my previous research with BC Cancer Agency is the notion of care coordination, a fundamental component of supportive care. Care coordination is an approach to care that attends to the unique needs of patients from the time of diagnosis through treatment and beyond across the following domains: practical, family (relationships), emotional, spiritual, physical, social, […]

Throughout Canada manufacturers and distributers of green roof and photovoltaic (PV) panels compete for installation projects on top of industrial, commercial and high-density residential rooftops. These technologies are often viewed as direct competitors as both systems reduce the environmental impact of buildings, albeit through different mechanisms, and consequently, rooftop designs rarely, if ever, apply both […]

Inflammatory bowel disease (IBD), encompassing Crohn’s Disease and ulcerative colitis, is characterized by chronic, relapsing, or progressive inflammation of the intestine. Canada has among the highest incidences and prevalence of IBD in the world with as many as 1 in 160 people with disease [1]. In ulcerative colitis, inflammation predominantly occurs in the epithelia cell […]

Accurate weather forecasts are extremely important when managing power production athydroelectric dams. BC Hydro uses weather forecasts to predict the amount of water flowing into reservoirs due to rainstorms and snowmelt. This project develops a system that improves these weather forecasts by correcting them based on how the forecasts performed in the past. The system […]

This project will assess the potential for using unmerchantable wood as feedstock for the production of biofuels and bioenergy. Large tracts of forests within the Great Lakes-St. Lawrence Forest (GLSL) consist of low quality pine- mixed woods that could supply feedstock if the unmerchantable wood were recovered in a sustainable and cost-effective manner. We will […]

The proposed project is aimed at developing a portable optical device to image blood flow velocity and oxygenation in a rat brain. The motivation behind this project is the development of minimally invasive method for long-term neurological studies in un-anesthetized animals, which should provide a better understanding of progression and treatment efficacy of various neurological […]

This research project will investigate local economic impacts resulting from municipal government procurement through locally-owned suppliers in comparison to procurement through national or multinational suppliers with local operations. The objective of the project is to determine a BC analysis to quanitify the economic impact of local purchasing decisions. Using the LM3 method, this research will […]

Although early clinical trials have been positive, peptide vaccine mechanism of action (how tolerance is induced) is unknown. The primary objective of these studies is to identify changes in gene expression and cytokine expression that are correlated with vaccine treatment. These changes could provide insight to mechanisms of action and may reveal potential genetic biomarkers […]

The somatic mutational processes that occur within human cancers generate novel, non-self proteins that have the potential to be detected by antibodies and therefore exploited therapeutically. Such antibodies can be generated through the stimulation of the immune system or through the synthetic generation of monoclonal antibodies (mAbs). The nascent ability to determine the complete transcriptomes […]

The intern will be engaged in developing a Lean and Green road map that establishes the current environmental performance of the study facility, identifies opportunities for improvement, and provides a systematic process in order to achieve sustainability goals. By engaging in the development of Current and Future Value Stream maps, applying relevant process management tools, […]

This SEF/MITACS proposal seeks to develop a curriculum about mining and local economic development. The content of the curriculum is divided into two main parts: a) mining life cycle and its phases and b) the opportunities that mining activities can create to local communities. The ultimate goal in developing this curriculum is to create a […]