G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs via a diverse array of stimuli as varied as photons, lipids, ions, small hormone or neurotransmitters through to larger peptidic […]

En recherche sur le cerveau, l’imagerie et la stimulation cérébrale sur le modèle animal sont des techniques de référence. Dans ces expériences, l’expérimentateur doit manipuler l’animal (la souris le plus souvent), ce qui réduit la qualité de données qui peuvent être collectées. Afin de dépasser cette limitation, une nouvelle stratégie d’acquisition basée sur des cages […]

One of the practical methods for treating powdery mildew is to use a UV lighting system carried by an autonomous robot. The height of the plants can be different from one greenhouse to another or even within the same greenhouse. Hence, having a varying-height UV lighting system would be essential. . To enhance the robot’s […]

Developing safer, more effective treatments for chronic pain has become a major area of research due to the negative side effects of opioids. This project aims to mediate the intelligent design and development of drugs, that will achieve pain relief without the detrimental side effects of addiction and respiratory depression. The proposed research will use […]

The advantages of digital data (signal functions) processing have made this technique a standard for processing real world analog data in many areas of life, from music industry to seismology. Stored digitally, the data also become less sensitive to physical limitations than their analog counterparts. Other advantages include straightforward low frequency filtering procedures (e.g. as […]

The cosmetics industry represents a market with sales of more than US 1 0 billion worldwide. It is estimated that sales of cosmetic products are expected to grow annually by more than 3.7% until 2022. Extremely dynamic with a development cycle of 1 months, this sector is also extremely regulated at the national level without […]

Environ 9% des personnes ayant une déficience intellectuelle (DI) atteignent les recommandations gouvernementales en termes d’ activité physique. Cette réalité est également observée par l’organisme sans but lucratif – Ma deuxième maison à moi – qui offre des services de centre d’activités de jour à des adultes présentant une DI. Une faible motivation à l’activité […]

Dans le cadre d’une restructuration, Orica souhaite réhabiliter une partie de son site localisé à Brownsburg-Chatham au Québec. Le site qui accueille depuis 1870 une usine de production d’explosif est non seulement contaminé, mais présente des risques importants pour les écosystèmes et la santé humaine. Ainsi, l’entreprise souhaite développer une approche verte qui vise à […]

We propose to develop in collaboration with Medtronic Canada a bioceramic drug delivery system for the local controlled release of Biphosphonates (BP) – drugs that prevent bone resorption – to promote both tumor inhibition and bone regeneration at the site of bone tumor resection, eliminating the need for high systemic doses and side effects associated […]

After legalisation, cannabis use has become more widespread, and consumption has increased in Canada. There is a need for more insight into the extent of impairment caused by cannabis in adults. The goal of this proposed research project is to determine the degree of impairment in adults after cannabis ingestion. We will study the effect […]

The use of business process modeling (BPM) and analytics has demonstrated exceptional results in improving efficiency and effectiveness in various industries. Health care processes however, are characterized by uncertain, exception and continual evolution. This project aims to apply flexible, adaptive and evolutionary process modeling protocols coupled with operations research and other analytic methods to the […]

Homelessness is a growing challenge in Canada, with devastating economic and social costs. Neuroscience offers important insights into the causes and consequences of homelessness. Individuals experiencing housing instability are more likely to have a history of brain injury and mental illness than the general population. These brain-based conditions can be associated with impaired cognition, which […]