Research and Development of Urinary Metabolome-based Personalized Health Assessment for Inflammatory Bowel Disease, Autism and Environmental Exposure – Year One

Despite the growing interests and publications in metabolomics, there is a significant gap between what have been found through scientific studies and what have actually been applied in clinical practice and preventative healthcare. This proposed project aims to fill this gap by addressing two major causes; 1) lack of utilization in existing metabolomics data and […]

Read More
Research and Development of Urinary Metabolome-based Personalized Health Assessment for Inflammatory Bowel Disease, Autism and Environmental Exposure – Year Two

Despite the growing interests and publications in metabolomics, there is a significant gap between what have been found through scientific studies and what have actually been applied in clinical practice and preventative healthcare. This proposed project aims to fill this gap by addressing two major causes; 1) lack of utilization in existing metabolomics data and […]

Read More
The correlation and validation of functional markers and biomarkers for m/sTBIpopulations during simple and complex tasks – Year 1

This project aims to develop and validate markers for adaptive neurological performance therapies for persons with moderate-to severe traumatic brain injury (m/sTBI), with the purpose to further develop clinical paradigms for at-risk populations. In order to accomplish this, we have formed a collaboration between two Universities (Université Laval and McGill University) and two industrial partners […]

Read More
Biomarkers for detection of breast cancer and multiple myeloma using liquid biopsy

Blood tests are highly sought after to enable earlier cancer detection. We previously developed a blood test for breast cancer that is in prospective clinical study in Alberta, Manchester (UK), Oklahoma (USA) and South Korea. The proposed project will investigate some clinical samples collected through this work to support the primarily focus of identifying biomarkers […]

Read More
Perioperative Opioid Usage Quality Improvement [CDTS-PDF1]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

Read More
Developing rAAV-mediated retinal gene therapy to improve vision for ZellwegerSpectrum Disorder – Year Two

Peroxisome Biogenesis Disorders of the Zellweger Spectrum (PBD-ZSD) are a group of inherited genetic disorders caused by mutations in any one of 13 PEX genes. Individuals with the common PEX1-G843D mutation consistently develop a retinopathy that progresses to blindness. To test whether we could slow visual loss in these patients, we performed a proof-of-concept trial […]

Read More
Perioperative Opioid Usage Quality Improvement [CDTS-PDF1] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

Read More
Perioperative Opioid Usage Quality Improvement [CDTS-PDF2]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

Read More
Perioperative Opioid Usage Quality Improvement [CDTS-PDF2] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

Read More
Photo-curable Polysiloxane Resins for Engineered Ferroelectret Films

Polymer ferroelectrets are light weight and flexible materials that display piezoelectric behaviour. These properties make them ideal for use as transducers in the aerospace industry. However, the traditional methods used to prepare high performance polymer ferroelectrets cannot be used for large scale manufacturing due to poor reproducibility or high cost. Furthermore, these manufacturing techniques rely […]

Read More