Development of a next-generation in vivo human gene-editing therapeutic platform – Year two

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

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Towards creating intelligent heat stress monitoring and management solutions to safeguard health and wellness

The scientific challenge for this research project is to advance our understanding of the impacts of heat stress in heat vulnerable workers and to use this information towards the creation of intelligent heat stress monitoring and management solutions to safeguard health and wellness. Currently, our understanding of the effects of heat exposure on vulnerable individuals […]

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Formulating a novel goat-whey based drink and studying its nutritional and health functions – Year two

This project will create novel goat milk-based products and test their health effects in healthy adults. Interest in goat milk is increasing, mainly due to two market trends: consumers’ new taste trends for niche/ethnic products, and the perception of goat milk having added health properties. Goat milk is perceived as having intestinal anti-inflammatory effects and […]

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Optimizing the placement of Med-El’s BoneBridge implant: image-guided positioning and biomechanical efficiency

Med-El’s BoneBridge implant provides the sensation of sound to hearing-impaired persons. The device’s transducer is surgically implanted in the skull. Key surgical problems are to find a location on the individual patient’s skull that is thick enough to house the transducer and to place and configure the transducer to maximize sound energy transfer to the […]

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Optimizing the placement of Med-El’s BoneBridge implant: image-guided positioning and biomechanical efficiency – Year two

Med-El’s BoneBridge implant provides the sensation of sound to hearing-impaired persons. The device’s transducer is surgically implanted in the skull. Key surgical problems are to find a location on the individual patient’s skull that is thick enough to house the transducer and to place and configure the transducer to maximize sound energy transfer to the […]

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Behavioural Economic Interventions to Promote Health and Wellness on a Canadian Mobile Health Application

Behavioural economics demonstrates that people consistently behave in irrational ways that lead to poorer health outcomes. Yet the way in which people behave irrationally is predictable, which governments and organizations around the world have used to design “nudges” to “[alter] people’s behaviour in a predictable way without forbidding any options” (Thaler & Sunstein, 2008). Carrot […]

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A mass balance modelling framework for chemicals and their primary metabolites for ecological and human health assessment

Chemicals manufactured and used in society degrade through physical and biological processes (e.g., photolysis, biotransformation) into break-down products (e.g., metabolites). Most “parent” chemicals can breakdown relatively quickly so that they are not persistent or bioaccumulative; however, some metabolites formed during the degradation processes can persist in the environment thus requiring consideration for ecological and human […]

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A mass balance modelling framework for chemicals and their primary metabolites for ecological and human health assessment – Year two

Chemicals manufactured and used in society degrade through physical and biological processes (e.g., photolysis, biotransformation) into break-down products (e.g., metabolites). Most “parent” chemicals can breakdown relatively quickly so that they are not persistent or bioaccumulative; however, some metabolites formed during the degradation processes can persist in the environment thus requiring consideration for ecological and human […]

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Development of a novel IPM strategy for brown marmorated stink bugs (Halyomorpha halys) using RNA interference (RNAi) technology

Brown marmorated stink bug (BMSB) (Halyomorpha halys (Stål)) is an invasive pest with a large host range that includes many economically important fruits, vegetables, and row crops. Native to Asia, BMSB was first detected in North America in 1998 and since has become established in British Columbia, Quebec, and Ontario; and 44 American states. In […]

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Development of a novel IPM strategy for brown marmorated stink bugs (Halyomorpha halys) using RNA interference (RNAi) technology – Year two

Brown marmorated stink bug (BMSB) (Halyomorpha halys (Stål)) is an invasive pest with a large host range that includes many economically important fruits, vegetables, and row crops. Native to Asia, BMSB was first detected in North America in 1998 and since has become established in British Columbia, Quebec, and Ontario; and 44 American states. In […]

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Land-based learning: Facilitating reconciliation & advancing the integration of Indigenous and Western knowledge systems

The Truth and Reconciliation Commission (TRC) (2015) report calls for the integration of Indigenous knowledge and teaching methods into educational curriculum. Critical to decolonizing education is reinserting people into relationships with the land as a mode of education, referred to as ‘land-based learning’. This proposed research project will establish best practices for the establishment of […]

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