The objective of this project is to develop lipid nanoparticle (LNP) reagents for the delivery of nucleic acids to turn off, or turn on target genes in “hard-to-transfect” neurons and stem cells in vitro and in vivo. A recent report (BCC Research, April 2011) observed that “51% of researchers employ cell-based techniques to perform transfection […]

The objective of this project is to develop lipid nanoparticle (LNP) reagents for the delivery of nucleic acids to turn off, or turn on target genes in “hard-to-transfect” neurons and stem cells in vitro and in vivo. A recent report (BCC Research, April 2011) observed that “51% of researchers employ cell-based techniques to perform transfection […]

This project combines two cutting-edge technologies, automated core scanning and artificial intelligence (AI), to improve the efficiency and accuracy of mineral processing in the mill as well as mine waste management. The goal is to streamline the process and ensure that the minerals are processed in the most effective way possible. Then, the objective is […]

Federal Canadian regulations of the Fisheries Act require operating mines and pulp mills to undertake biodiversity monitoring every three years to assess potential environmental effects. Different groups of organisms have differential sensitivity to pollutants and other environmental factors, so communities (e.g., invertebrates) provide a rich source of information about the system’s health Identifying invertebrates using […]

The high prevalence of obstructive sleep apnea (OSA) poses a serious threat to the healthy growth and development of many children. The lack of oxygen during sleep can lead to daytime sleepiness, growth failure, behavioural problems and developmental delay. Polysomnography (PSG), the gold standard to diagnose OSA is high in cost, requires a well-equipped sleep […]

Nowadays, the electrical systems have thousands of nodes. To simulate this kind of systems electromagnetic transient programs (EMTP) are often used. One of the widely used commercial programs available is PSCAD, which can simulate large networks. However, these kinds of systems could impose an important computational burden, and use a considerable amount of time to […]

The high prevalence of obstructive sleep apnea (OSA) poses a serious threat to the healthy growth and development of many children. The lack of oxygen during sleep can lead to daytime sleepiness, growth failure, behavioural problems and developmental delay. Polysomnography (PSG), the gold standard to diagnose OSA is high in cost, requires a well-equipped sleep […]

Confidential data is one of the most precious assets large organizations can have and data theft can be embarrassing and costly. In this research we will carry out innovative research on detecting employee accounts that are exhibiting risky behaviour that may lead to leakage of data, whether carelessly or through malicious intent. It is difficult […]

Screening with low-dose CT has been shown to significantly reduce lung cancer related mortality in high-risk ever-smokers. Interval cancer (IC) is a rising challenge in lung cancer screening because it usually presents in an advanced stage (stage III/IV non-small cell cancer) or is more biologically aggressive (i.e., small cell histology) and have a poorer prognosis […]

“Le concert augmenté” est un projet pionnier de recherche-création qui prévoit, pour la première fois d’une façon structurée, l’utilisation des nouvelles technologies audio (les écouteurs à conduction osseuse) dans le contexte de concert de musique électroacoustique. Ce nouveau médium de diffusion permettra des expériences de concert en réalité augmentée sonore, c’est-à-dire des performances immersives où […]

Tel qu’il a émergé dans la Silicon Valley autour du modèle de la « start-up », le monde de l’entrepreneuriat numérique s’est fondé sur des valeurs d’ouverture, d’inclusion et de liberté, laissant imaginer le respect d’une égalité professionnelle. Pourtant, alors que l’écosystème des start-up québécois est en pleine expansion, les femmes ne représentent que 15 […]

Seasonal influenza causes significant mortality and morbidity worldwide, and we are currently unprepared to mitigate a fatal pandemic outbreak like the 1918 Spanish Flu. A proven influenza antiviral target is the M2 viroporin, or viral ion channel. Amantadine, an M2 inhibitor was an effective antiviral for 20 years. However, current influenza antivirals are increasingly ineffective […]