Uncovering the role of ketogenesis in SGLT2 inhibitor-mediated fatty liver disease

Fatty liver disease, the most common complication of type 2 diabetes (T2D), affects 1 in 5 Canadians. If not managed or treated, a proportion of patients with fatty liver disease may develop the irreversible phases of liver failure, and hepatocellular carcinoma. A new class of drugs, SGLT2 inhibitors (SGLT2i), has been approved by Health Canada […]

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Développement de vaccins multivalent vivant atténué contre les infections respiratoires causées par les Escherichia coli pathogènes aviaires

Les Escherichia coli pathogènes aviaires (APEC) sont des pathotypes particulièrement importants pour l’industrie avicole, car il provoque la colibacillose, une maladie entraînant des pertes économiques importantes en raison de la mortalité et/ou de la baisse de productivité des oiseaux affectés. Étant donné que plusieurs souches d’APEC sont impliquées dans les épidémies, le développement de vaccins […]

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Peptide-based material for heart muscle repair

With over 17 million deaths per year, heart diseases remain the top cause of mortality worldwide. Surgeries such as bypass restore blood supply and save lives. However, after a heart attack the capacity of the heart to pump blood is reduced. In Canada, over 2 million people aged 20+ live with heart disease, costing the […]

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Focused Ultrasound for Intraocular Hemmorhage

Intraocular hemorrhage is the most common cause of sudden vision loss from advanced diabetic eye disease. This occurs when blood from diseased retinal vasculature leak into the normally clear, gel-like substance in the eye called the vitreous, obscuring vision. The current management guidelines for these patients is a period of modified bedrest (up to 4 […]

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Non-destructive testing of utility poles in service

Wooden utility poles provide safe, economic, easily obtainable means of delivering power, communications, and cable television to the masses of industrial and residential locations worldwide. However, when a pole has been in service for a substantial number of years, its failure becomes more likely. Hence, the proposed project focuses on the strength estimation of in-service […]

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Using artificial intelligence to screen children suspected with listening difficulties

The goal of this project is to create a cutting-edge screening tool for children with listening difficulties, which can have a profound impact on their academic performance, social development, and overall well-being. Despite the current assessment process, which is time-consuming and requires extensive training and experience, early identification and intervention are critical for these children […]

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Development and Evaluation of Antimicrobial Agents for Improving the Lifetime of Metalworking Fluid

Metalworking fluid is a widely used lubricant during the processing of metal (drilling, cutting, grinding, etc.). Even though it has been applied to industries for decades, microbial contamination is still considered a major problem during its application. The microbial contaminations not only reduce the effectiveness of the lubrication but also cause potential health issues. In […]

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Social Innovation Researcher in Residence – Zero Emissions Innovation Centre of Metro Vancouver

Metro Vancouver’s new Zero Emissions Innovation Centre’s (ZEIC) mandate is to catalyse, accelerate, and scale climate action innovation across Metro Vancouver through program delivery, impact investing, granting, partnerships, capacity building, and research. With the urgency and importance of city-led climate action rapidly increasing, and the impacts of a changing climate being directly experienced by communities […]

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Human-in-the-loop artificial intelligence for identification of fish behavior with high-frequency periodic acoustic fish tags

Innovasea produces fish tags and receivers to track the presence and motion of fish and marine mammals while underwater. Fish tracking (acoustic telemetry) is used by researchers worldwide to determine the abundance and habits of marine life, make decisions about fishing seasons and allowed catches, and help protect marine mammals. Innovasea has developed a novel […]

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