Implication of Epigenetic Dysregulation in Early Embryo Development

The project aims to identify the interdependence that exist between epigenetic modifications that regulate gene expression, as well as their susceptibilities to permanent disruption following errors in the embryonic program. We use an innovative embryonic stem cell model in which the expression of an epigenetic enzyme responsible for DNA methylation can be controlled. We will […]

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Development of novel nonlinear time-tenses for ultrafast signal processing applications

Manipulation and characterization of ultrafast optical signals are fundamental procedures for a wide range of applications, including telecommunications, biology, quantum information science, spectroscopy, and atomic and molecular physics. In this context, the so-called theory of space-time duality offers a powerful framework for the development of important optical signal processing functionalities. One of its key elements […]

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HUMAN beIngS trafficking and Minor sexual exploitation (HUMANISM)

Human trafficking and sexual exploitation are serious and complex issues affecting millions of children around the world. Unfortunately, scientists, Child protection workers (CPWs), law enforcement personnel, and other experts are currently struggling to effectively prevent these crimes and ensure the rehabilitation of vulnerable children. One of the main hurdles impeding their efforts is the current […]

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Allele specific re-establishment of imprinted DNA methylation using epigenome editing

Through unknown mechanisms, parent-of-origin-specific methylation marks on one allele of imprinted genes are able to escape the embryonic reprogramming wave occurring during the first week of development and retain their profiles via DNA methylation maintenance activity. Failing to maintain proper genomic imprinting patterns during the embryonic reprogramming leads to various abnormal developmental delay. What remains […]

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Gestion durable des eaux pluviales en milieu urbain

L’objectif des travaux de recherche entrepris lors du séjour à l’étranger est de de mieux comprendre comment le contrôle en temps réel du réseau de drainage (contrôle intelligent des infrastructures de drainage) influence la conception des ouvrages de contrôle à la source (comme les infrastructures vertes visant à faciliter l’infiltration et l’évaporation de l’eau pluviale […]

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Effects of sedation with dexmedetomidine-butorphanol and general anesthesia (propofol-isoflurane) on the Feline Grimace Scale scores

The Feline Grimace Scale is a validated tool that uses changes in facial expressions for acute pain assessment in cats. The tool is a valid, reliable, sensitive and specific for feline acute pain recognition for various types of painful conditions (www.felinegrimacescale.com). The aim of this research project is to assess the effects of sedation and […]

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Flame synthesis of nanomaterials: The agglomeration of nanoparticles interacting via short-/long-range potentials

The agglomeration of nanoparticles under flame conditions is numerically simulated. The focus is placed on the interaction forces between particles. These forces are suspected to play an important role on the agglomeration rate, agglomerate’s geometry, and particle size distribution. This is particularly important in the context of aggregates (chemically bound nanoparticles) or agglomerates (physically bound […]

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Hierarchical Bayesian Optimization in Neurostimulation

Neuroprostheses interfacing with brain and spinal tissue are in rapid development and are being applied to clinical treatment of paralysis after spinal cord injury stroke and other neurological disorders. We have developed a versatile intelligent neuroprosthetic agent, a Gaussian Process (GP)-based Bayesian Optimization (BO) approach. We have further laid the theoretical groundwork to cover larger […]

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The World as Sacrament: the Eucharistic Ontology of Maximos Confessor

My proposed project consists in completing the final chapters of my doctoral dissertation: The World as Sacrament: The Eucharistic Ontology of Maximos Confessor. In essence, I argue that Maximos’ insistence that all things are created from God (ek theou) according to (kata) the Logos offers a powerful example of sacramental ontology – that is, a […]

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Réalisation d’une frise chrono-systémique de la vulnérabilité aux aléas côtiers du Pays bigouden (France)

Ce stage s’insère dans le cadre du projet de recherche ARICO : Co-construction de scénarios d’Adaptation des territoires maritimes aux RIsques COtiers dans un contexte de changements climatiques en France et au Québec. Le stage visera à proposer une méthodologie pour construire des frises chrono-systémiques de vulnérabilité adaptée pour les territoires québécois et français soumis […]

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The Literary Economy of Migration in Postcolonial E-fraud Literature

The project examines internet fraud as a practice engaged in by individuals who are economically disadvantaged, are unable to find regular jobs, and are not able to migrate to developed countries where work might be found, often because of border restrictions that exclude them. It proposes to study how literary writers have been thinking about […]

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