Genetic modifiers in neurodevelopmental diseases: a C. elegans high-throughput forward genetic screen to identify suppressors of alg-1/AGO1

Rare diseases, despite being individually rare, cumulatively affect millions of people around the world. Over the last decades, high throughput sequencing elevated diagnostic success in rare diseases from ~10% to ~45% but have stalled at ~45% since. One reason for that may be that clinical presentation of the disease-causing alteration(s) could be highly variable. Some […]

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Glycopolymer based Silicon Quantum Dots – Functionalization and Biological evaluation

Silicon quantum dots (SiQDs) are semiconductor nanoparticles with sizes ranging from 1 to 10 nm that show great promise for photonics, microelectronics, and fluorescent bio-imaging considering their ability to fluoresce from blue to near infrared light. In comparison to conventional quantum dots (which can release toxic metals), Si quantum dots are expected to be safer […]

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Implementation of CRM Workflow Process Improvement & Expansion

Now that DEAN Financial has implemented a new CRM system, we need to fully utilize its tools to mine data and make better use of our existing client and prospect base. This project proposes that the co-op student assist in data mining our CRM, which currently holds approximately 1,200 clients and over 1,900 prospects. The […]

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Scoliosis management through novel asymmetry surface topography analysis

Scoliosis is a condition where the spine curves abnormally, often developing in children and adolescents. To monitor how scoliosis progresses, patients usually have repeated x-rays over several years, sometimes as often as every six months. While this helps doctors track changes in the spine, it also means children are exposed to repeated radiation during an […]

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Research and Development of a Novel Natural Health Product for Pain Relief

This project aims to characterize and standardize Relief Mx, a liquid designed for pain management. Relief Mx combines traditional Chinese medicine with modern pharmaceutical components as an alternative to steroid-based nerve block treatments. The formulation includes active ingredients extracted from four herbal medicines: Achyranthes bidentata, Scrophularia ningpoensis, Lonicera japonica (honeysuckle), and Dendrobium. This study will […]

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Novel next-generation large diameter fiber reinforced polymer piping

This project addresses the significant demand for composite piping capable of withstanding elevated temperatures and/or pressure in water service and oil and gas transportation. In collaboration with Flexpipe at Mattr Infrastructure Technologies, we aim to develop rapid testing methods for designing and manufacturing large-diameter spoolable fiber-reinforced composite piping. Our focus is on exploring alternative procedures […]

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Estimating Risk and Testing Based on Change for Assets, Visual Code, and Textual Code

Video games are complex data driven software systems. The data is the levels and objects inside of the levels. These objects are programmed using visual programming languages and textual programming languages. Current software engineering support for visual languages is in its infancy and the tools that software engineers rely upon are often not available in […]

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A Wearable Electrical Vestibular Stimulation System for Tracking and Enhancing Human Balance and Gait

The vestibular balance system detects linear and angular head motion and plays a role in stabilization of human balance and walking. Age-related vestibular disruptions increase fall risks for a large fraction of our elderly populations and make it increasingly difficult to continue living activity and independently, both of which have very large associated healthcare costs. […]

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Impacts of Climate Change on Convective Storms in the Canadian Prairies using Numerical and Statistical Downscaling Techniques

Convective storms bring heavy rainfall, thunderstorms, and sometimes hail, posing significant risks to cities, farms, and infrastructure. These intense storms are especially common in Canada’s Prairies during the summer and are becoming more severe with climate change. To better predict these storms, we need detailed climate models because convective storms usually happen over small areas […]

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My Heart Coach – a nested pre-/post-, multi-methods study

Patients with cardiovascular disease benefit from participating in cardiac rehabilitation which have been traditionally offered in-person. Patients find these to be challenging to attend and may not complete the programs if they enroll. Providing cardiac rehabilitation as an online program is a promising solution. My Heart Coach is an online web-based multimedia program for cardiac […]

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