Mathematical Models of Oncolytic Virotherapy Including Oxygen Dependent Phenotypic Adaptation

This project develops mathematical models to investigate how tumour heterogeneity and oxygen availability influence the efficacy of oncolytic virotherapy (OVT). OVT employs genetically engineered viruses to selectively infect and destroy cancer cells, yet its therapeutic success is often hindered in hypoxic tumour regions, where low oxygen levels promote cellular adaptations that reduce viral replication and […]

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Improving the flame resistance of lyocell fibres using nanoparticles

Worldwide demand for man-made cellulosic fibres is increasing as availability of cotton fibre is limited. The regenerated cellulose lyocell process offers large advantages over other processes in terms of environmental and social impacts. However, cellulose is flammable. Current strategies to prepare flame-resistant (FR) regenerated cellulose fibre involve the incorporation of a fine powder of organophosphate […]

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Glycoproteomic analysis of erythrocytes and PBMCs

The healthcare system relies heavily on blood and blood products for a large variety of life-saving treatments. However, blood products are perishable and have short shelf lives. Given the continuous demand for these products, this issue must be addressed. As blood is stored, the profile of cell surface sugars, known as glycans, has been shown […]

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Development of a unique natural product catalogue through chemical characterization of Canadian wild plants

The proposed research aims to investigate and chemically characterize Canadian wild plant species. Natural products from plants are valuable to many industries and for promoting health and wellness. Certain plants that flourish under the conditions found in the Canadian prairies are likely to be rich in valuable chemical compounds. The research will be conducted by […]

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Enhancing Digital Marketing and Business Intelligence for Hyspecs Eyewear – Part II

This project will enhance Hyspecs’ digital marketing and e-commerce operations through four key initiatives: streamlining the migration to a new email marketing platform with automated flows to better engage customers; creating a strategic sales and media calendar to align campaigns across channels; scaling up paid advertising using data-driven insights to boost performance and reach; and […]

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Fraud Detection in Financial Graphs

A significant amount of fraudulent activity tends to go unreported in reality, one of the major focuses for our team recently has been to develop robust GNNs that can perform anomaly detection on noisily labeled graphs. Noisily labeled anomalous data can reduce the model performance as it learns incorrect patterns during training, cause the model […]

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L2M – NeviSight

NeviSight is an AI-powered platform that transforms retinal imaging into faster, more accurate, and more accessible eye disease detection. Designed as a decision-support tool, it aims to integrate seamlessly with existing fundus cameras and clinical workflows, providing clinicians with real-time lesion segmentation and risk insights. Our completed prototype combines a proprietary hybrid AI model with […]

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Development and Characterization of Zr-Doped Multifunctional High-Entropy Alloy Coatings

This project aims to develop multifunctional high-entropy alloy (HEA) coatings that protect industrial components from multiple types of damage at the same time, including erosion, corrosion, and hydrogen attack. Using laser-directed energy deposition (L-DED), the research will study how adding zirconium to AlCoCr2FeMo0.5Ni –Zrx changes the coating’s microstructure and improves its performance for real industrial […]

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NouLife: Synthesis of Linked Conjugates

In 2023, Innovotech acquired a 60% interest in NouLife Sciences Inc., a company that developed the intellectual property for the linking of two antioxidant molecules commonly used in skin care products – alpha lipoic acid and acetyl-L-carnitine – into one molecule. The linking of the two molecules has been indicated by NouLife to increase the […]

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