Blood pressure increases with age in Western societies; however, populations that live as hunter-gatherers and subsistence farmers rarely develop cardiovascular disease and do not have age-related increases in blood pressure. The mechanisms responsible for the maintenance of cardiovascular health with aging are not clear. A mismatch between the conditions that postindustrialized populations inhabit – low […]

Climate change is rapidly altering the planet, and solutions are urgently required to reduce greenhouse gas (GHG) emissions and limit further warming. Blue carbon ecosystems (salt marshes, seagrass meadows, kelp forests, marine soft sediments) are important carbon reservoirs that could contribute to Canada’s climate change solutions. Yet, despite having the world’s longest coastline, Canada has […]

A Canadian-based company, Terrasol Geosolar Inc., has identified a unique opportunity to offer hurricane-resistant solar energy infrastructure for weather-ravaged areas of the world. Towards this functionality, there has also been significant market incentives to include bio-derived composite materials within the structure. However, current developments of natural fibre reinforced composites (NFRCs) in structural applications has been […]

Occupant thermal comfort and ventilation drive the operation of HVAC (heating, ventilation, and air conditioning) systems in buildings, which consume a large portion of their energy use. “Human-in-the-loop” (HITL), a term borrowed from machine learning referring to a synergy between humans and machines, is a data-driven approach that aims to enable human-based controls of the […]

The project aims to better understand how stress hormones (i.e., glucocorticoids) are synthesized in the thymus, a key primary lymphoid organ of the immune system. Stress hormones are critical for proper thymic development and immune function. However, many details about how and where in the thymus stress hormones are produced remain unexplored. As part of […]

With the rapid growth of sensors in Cyber-Physical Systems such as clinical data, industrial systems and data centres, there is an increasing need to monitor these devices to secure them against anomalies. This is particularly the case for streaming clinical data. Indeed, the timeliness revelation of anomalies in these data can save the patient’s life. […]

The goals of this proposal are to develop methods to identify cell subgroups in dopaminergic (DA) neuron cultures obtained by differentiation of human pluripotent stem cells (hPSC), and to exploit this information to improve existing DA neuron differentiation protocols. To realize these goals, we will leverage expertise at STEMCELL Technologies in hPSC differentiation and Simon […]

In the proposed project, we will investigate a solution for increasing the safety of construction workers at heights using an intelligent sensor-based system. A real-time monitoring system will be developed for alerting workers who are getting close to hazardous conditions and areas. The objective is to lower the chance of accidents by enhancing supervision of […]

Demand for aluminum alloys is increasing rapidly, facilitation of electric vehicles being but one example. A consequence is increasing scrap supply; a positive as aluminum is highly recyclable with it consuming a fraction of resources compared to using primary aluminum. There is a growing concern, however, as high-performance alloys are compositionally tuned to maximize performance. […]

Nitrogen is a key component in many molecules used as medicines, materials and fertilisers. Adding nitrogen into molecules is currently inefficient and expensive: it requires multiple steps and creates a lot of waste. Alternatively, it is possible to introduce nitrogen by processes called hydroamination and hydroaminoalkylation. These reactions are 100% atom efficient (all of the […]

The COVID-19 pandemic and corresponding health, social and economic implications have resulted in significant life changes for youth. One of the most critical impacts has been on youth mental health and wellbeing. To address the mental health needs of diverse youth populations during and following the COVID-19 pandemic, the proposed internship will advance the CIHR-funded […]

Recently, a new form of organization—a decentralized autonomous organization (DAO)—has emerged as a novel form of governance. DAO is an organization represented by programmed operating rules that determine who can execute changes to the rules of applications built on blockchains. Through ownership of governance tokens, DAO grants its stakeholders such as users, developers, and contributors […]