Crystal shape and size are among the most important features of crystalline product that are prevalent in the pharmaceutical industry. Extremely fine and needle-like crystals pose various problems in the downstream processes including filtration, tableting, handling, and storage. Rufinamide is an anticonvulsant medication, and its most stable and therapeutically advantageous crystalline form shows notoriously undesirable […]

Here at Mastercard, we have a transaction data where an account (card holder) transacts at a merchant, this data can be viewed as a Bipartite Graph of account and merchant nodes, where each edge represent a transaction between them. We have multiple models/tasks that provide predictive intelligence at an account level, e.g., predicting an account […]

Antibiotic resistance is a major threat to the health of Canadians. The spread of antibiotic resistance organisms and lead to inappropriate antibiotic treatment and adverse health outcomes. With this project, one intern will be supported to learn and develop approaches for rapid bacterial diagnostics and surveillance, with direct relevance for knowledge translation and knowledge generation. […]

The financial implications of time lost from work due to disability can be severe. Disability insurance coverage plans protect people from possible loss of income. We have found factors that predict the duration of disability benefit claims. However, it remains to be seen whether these associations are consistent. Improved understanding of modifiable factors associated with […]

At present, networks for the studying of fashion exist globally in Europe, the United Kingdom, and the United States, among others. Canada, too, is home to some of these collaborative sites, for example the Canadian Fashion Scholars and the Canadian Arts & Fashion Awards. Many of these networks have flourished through the publishing of an […]

Russian invasion of Ukraine began in February 2014 after Russia’s illegal annexation of Crimea. A larger invasion took place on February 24, 2022. Both conflicts have caused the displacement of 8 million Ukrainians to date. This is the largest humanitarian crisis in history since World War II. A significant percentage of these Ukrainian refugees have […]

Being physically active is associated with many health benefits. To help guide people on how much activity they need for optimal health, the Canadian Society for Exercise Physiology developed new Canadian Physical Activity Guidelines for all age groups. Specifically, this work will look at assessment, awareness, and uptake of the new guidelines as it relates […]

This research aims at investigating the structural performance of engineered bamboo composites (EBCs), namely Dragonwood, to replace traditional Canadian and tropical hardwoods used in jacking applications. Key mechanical properties and failure modes will be documented. The durability and flammability of all three materials will also be evaluated. Despite the obvious environmental advantages of EBCs (e.g., […]

Alkynamides are very promising inhibitors of tyrosine kinases, important enzymes that can cause cancer when being too active in cells due to different mutations. While being important moieties, until recently there was no convenient method to synthesize them using carbamoyl fluorides — most protocols use either dangerous or expensive and ecologically unfriendly reagents, which always […]

Financial fraud is a very serious problem plaguing financial institutions. Recent advances in information technology have only exacerbated this problem. Poor risk models were at the core of the 2008 financial crisis. Complex networks, structured graphs, are powerful models for representing higher-order interactions or dependencies within data sets. Graphs are relational models of covariates, where […]

Embedded in the surface of a virus, are different types of proteins that the virus uses to enter a host cell. These so-called viral glycoproteins are pivotal targets of the host antibody response to fight a viral infection. In recent decades, it has become clear that certain viral glycoproteins have evolved clever ways to suppress […]

Polyurethanes are an important class of synthetic polymers with widespread applications in consumer products. The origins of most of these products are derived from petrochemicals, and these traditional polymers are non-degradable and have limited recyclable potential. There is a need in this industry to endorses the practice of conserving resources, minimizing the environmental, health impacts […]