Development of femtosecond/picosecond laser and sample delivery for PIRL-DIVE-MS to enable spatial imaging of tissue and earliest possible detection of disease

Picosecond InfraRed Laser (PIRL) technology has finally realized the long-held promise of the laser to achieve the fundamental (single cell) limit to minimally invasive surgery – with the unexpected benefit of scar free healing. The very process of laser cutting involves the selective excitation of natural occurring water inside tissue to drive molecules into the […]

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Development of a Natural Language Processing algorithm for the topic and novelty identification of scientific articles

Currently the selection of peer reviewers is a secret process entirely controlled by journal editors. This introduces significant biases into the process that fosters an environment that contravenes every aspect of equity, diversity and inclusivity, inhibits novel ideas and suppresses creativity which is just bad for science as a whole. Furthermore, research is most often […]

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Immunotherapeutic targeting of CD133 in adult brain tumors and understanding tumor microenvironment in Glioblastoma

Glioblastoma (GBM) is an aggressive adult brain tumor, and in spite of standard of care (SOC) with radiation therapy and chemotherapy with temozolomide tumor re-growth (or recurrence) and patient relapse are inevitable. There is compelling evidence that suggests SOC can debulk the tumor but cells endowed with treatment-resistant properties (e.g. expressing the protein marker CD133) […]

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Spatial dynamics of sound beams in echolocating bats

This proposal uses advanced techniques in sound recording and analysis, statistics, and scientific computing to measure how echolocating bats adjust signal strength and the spatial geometry of their sonar beam to aid in auditory perception. A second but related project will compare vocalizations of young bats at different developmental stages and measure developmental changes in […]

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Effect of Saccharomyces boulardii CNCM I-745 in the prevention gluten immunopathology.

The only treatment for celiac disease (CeD) is a strict gluten-free diet, which is very difficult to follow. Despite following gluten-free diet, many celiacs experience ongoing inflammation and symptoms, highlighting the need for additional therapies. We have shown that celiacs have an altered composition of bacteria in their gut, and this leads to defective bacterial […]

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International Space Station Hemp Seed Germination- On Ground Proof of Concept

This project investigates the feasibility of growing cannabis (Hemp) in space on the International Space Station. Hemp represents an ideal crop due to it being a highly productive species creating significant amounts of oxygen, essential nutrients, and various products (including textiles, oils, and plastics if processed). As human space exploration increases in frequency and reaches […]

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Anode and solid electrolyte interface engineering

In our project, we plan to improve the interfacial properties between metallic Li anodes and garnet-based Li7La3Zr2O12 (LLZ) electrolyte. The approach is to use coating techniques such as chemical and physical vapor deposition (CVD/PVD), and atomic layer deposition (ALD) to deposit a thin protection layer on a dense LLZ separator which is co-sintered with a […]

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Hyivy device as non-hormonal therapeutic for endometriosis

Hyivy Health and McMaster University are collaborating on a research study around the effects of the Hyivy Therapy Device as a non-hormonal therapeutic for people with endometriosis. The goal is to track the effects on chronic pelvic pain while exploring the impact on quality of life, usability, and sexual function. Results of this study will […]

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Business Analyst (BA) Impact on Business Agility and Data Analytics

Digital Transformation of business, combined with globalization through outsourcing, has create an increasingly fast-paced, competitive environment for most businesses. Additionally, new disruptive technologies such as Artificial Intelligence and Blockchain are just beginning to open new opportunities for the next wave of Digital Transformation. Agile concepts have accepted in information systems (IS) development for more than […]

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Guidelines for Evaluating Service Programming for Autistic Adults: A Patient-Oriented Perspective on Service Evaluation using Functional Criteria

Currently there are few standards for evaluating service delivery, and since health care service delivery is a domain of the provinces, new health care services need to be tested and evaluated in each province before being widely offered. This leads to inefficiency in evaluations as well as unequal access to new services across the country. […]

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Proof of Concept Electrical and Colorimetric Detection of Bacteria and Bacteriophages using Molecularly Imprinted Polymers in Microfluidic Sensors

The COVID-19 pandemic has affected the whole world by the spread of a new respiratory virus (SARS-CoV-2), posing a significant burden on the society and the health system. Rapid and selective detection of pathogens, like SARS-CoV-2 virus, in clinical samples, food, water and the environment at large is crucial in diagnosis and breakout prevention. Conventional […]

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Using AI to Help First Responders Assess Skin Burns

Burns are a common type of skin injury that cause numerous deaths around the world every year. Timely assessment of burns plays an important role in a successful treatment. Traditionally, burns are assessed through visual and tactile observation by clinicians. This method of assessment is highly inconsistent as it depends on the availability of a […]

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