Single domain antibodies (sdAbs) represent a versatile class of heavy chain antibodies lacking a paired light chain and encoded by VHH germline genes typically expressed in camelids. KisoJi Biotech has developed a transgenic mouse line in which each mouse expresses multiple camelid VHH genes capable of specifically binding any antigen of interest. The small molecular […]

Single domain antibodies (sdAbs) represent a versatile class of heavy chain antibodies lacking a paired light chain and encoded by VHH germline genes typically expressed in camelids. KisoJi Biotech has developed a transgenic mouse line in which each mouse expresses multiple camelid VHH genes capable of specifically binding any antigen of interest. The small molecular […]

In my PhD dissertation, I proposed a renewed theory of the “narreme” – the minimum basic unit of narrative structure, a concept which originated in the 1960s but which has been largely neglected since then. I suggested that a Narreme Theoretic approach could be tremendously useful not only for the purposes of narrative analysis, but […]

In my PhD dissertation, I proposed a renewed theory of the “narreme” – the minimum basic unit of narrative structure, a concept which originated in the 1960s but which has been largely neglected since then. I suggested that a Narreme Theoretic approach could be tremendously useful not only for the purposes of narrative analysis, but […]

A wide range of cognitive faculties are commonly compromised in numerous trauma-exposed populations, leading to impaired functioning, and reduced treatment response rates. There is a dire need for novel therapies that can directly target such deficits in top-down cognitive control. Goal management training (GMT) is one such cognitive remediation therapy found to be effective for […]

Imaging of cerebral perfusion (the delivery of blood to a capillary bed in the brain tissue) is significant for diagnosing a variety of diseases. There are multiple challenges associated with perfusion imaging which significantly limits the quality of cerebral perfusion images. I am planning to develop a novel approach of cerebral perfusion magnetic resonance imaging […]

Sudden Unexpected Death in Epilepsy (SUDEP), the commonest cause of death in epilepsy, is the most feared complication. SUDEP usually occurs following a seizure, most often in patients who are non-responsive to antiepileptic drugs. These patients are typically found dead in bed following respiratory apnea and cardiac arrest. Our group has shown that seizures in […]

To combat the degradation of receiving water resulting from stormwater runoff approaches that focus on retaining and infiltrating stormwater at the source, referred to as Low Impact Development (LID) practices, are being proposed more frequently in recent years. Toronto and Region Conservation Authority recently initiated monitoring of precipitation and runoff from a large industrial site, […]

This MITACs Globalink award will be used to support research into small-scale and run-of-river hydropower currently being deployed in Europe and potentially feasible for deployment in Northern Ontario semi-frozen off-grid locations. The world leaders in small hydropower R&D are in Europe. France in particular is well recognized as a global leader in all aspects of […]

Currently, the global warming alerts, oil prices fluctuations and clean energy have paved the way of investing in the producing wells by enhancing the recovery of hydrocarbons compared to exploration wells. Applying hydraulic fracturing from injected fluids is most common method used. These fluids create cracks in the bedrock and push the hydrocarbons to the […]

The global burden of hepatocellular carcinoma (HCC) is increasing as it has become the second leading cause of cancer-related deaths and the fifth most common cancer worldwide. HCC is heterogenous, arising in the setting of various chronic liver diseases such as hepatitis C, non-alcoholic fatty liver disease and cirrhosis. Patients with cirrhosis who develop cancer […]

The global burden of hepatocellular carcinoma (HCC) is increasing as it has become the second leading cause of cancer-related deaths and the fifth most common cancer worldwide. HCC is heterogenous, arising in the setting of various chronic liver diseases such as hepatitis C, non-alcoholic fatty liver disease and cirrhosis. Patients with cirrhosis who develop cancer […]