Many human genetic diseases are associated with defects in post-transcriptional gene regulation and alternative splicing. Despite rapid technological advancements, successful diagnostic rates for rare genetic disorders are still low and clinical interventions and treatments unavailable for most patients. This project aims to address this challenge by developing novel antisense RNA therapies based on the splice-switching […]

Superalloys are a group of high-perfornlance alloys which are widely used for high stress, high temperature, and severe wear and erosion/corrosion environments. Erosion and corrosion constitute one of the most challenging problems limiting the service lifetime of superalloys. However, due to the complexity of testing procedures and multiplicity of affecting factors as well as the […]

Driven by climate change induced water scarcity, further enhanced by rapid urbanization and population growth, potable water reuse initiatives are gaining interest. Potable reuse involves the indirect or direct use of highly treated municipal wastewater as a municipal drinking water source. Historically, the most commonly installed potable reuse train consisted of microfiltration, reverse osmosis (RO), […]

Driven by climate change induced water scarcity, further enhanced by rapid urbanization and population growth, potable water reuse initiatives are gaining interest. Potable reuse involves the indirect or direct use of highly treated municipal wastewater as a municipal drinking water source. Historically, the most commonly installed potable reuse train consisted of microfiltration, reverse osmosis (RO), […]

Glioblastoma multiforme (GBM) (the deadliest form of brain cancer) is associated with poor survival rates (approximately 12-15 months from the time of diagnosis). This is due to the fact that most cases of GBM are resistant to current standards of care. As a result, novel effective treatment options are highly desirable. It has recently been […]

The ability to correctly make safety-related decisions and to demonstrate compliance with existing limits is of great importance in the nuclear safety analysis industry. For example, we may be interested to assess whether or not a physical component (such as the pressure tube which carries fuel) has undergone physical changes that have exceeded its allowable […]

Cellulose is a commercially important biopolymer. Due to its abundance, biocompatibility and renewability it has shown important commercial applications in food, pharmaceuticals, biomedical. Depending on the origin and the processing methods used, the resulting fiber dimensions, structure, crystallinity and molecular weight (MW) can vary over a broad range. MW is one of the most important […]

Cellulose is a commercially important biopolymer. Due to its abundance, biocompatibility and renewability it has shown important commercial applications in food, pharmaceuticals, biomedical. Depending on the origin and the processing methods used, the resulting fiber dimensions, structure, crystallinity and molecular weight (MW) can vary over a broad range. MW is one of the most important […]

The wide adoption and development of wireless sensing technologies for the monitoring and autonomous identification of financial activities have affected financial institutions in the past decade. However, wider utilization of RFID technologies in the banking sector has introduced challenges regarding the security and privacy of sensitive financial data. The proposed innovations and technological developments will […]

The wide adoption and development of wireless sensing technologies for the monitoring and autonomous identification of financial activities have affected financial institutions in the past decade. However, wider utilization of RFID technologies in the banking sector has introduced challenges regarding the security and privacy of sensitive financial data. The proposed innovations and technological developments will […]

Brain tumours, including ependymoma, are some of the most difficult cancers to treat. Although the past few years have seen many exciting advances in characterizing these brain tumours, there are few effective therapies available for patients, many of whom are children and young adults (and for whom long-term side effects can be extremely damaging). Until […]

Brain tumours, including ependymoma, are some of the most difficult cancers to treat. Although the past few years have seen many exciting advances in characterizing these brain tumours, there are few effective therapies available for patients, many of whom are children and young adults (and for whom long-term side effects can be extremely damaging). Until […]