Septic shock is an acute pathology that is the leading cause of admission to ICUs across Canada, and the developed world. Unfortunately, no treatment to date has yet to be proven beneficial. Cardiac failure is a major factor in the mortality induced by septic shock. A major player to be targeted in treating this dysfunction […]

As a central problem in modern microeconomic theory, multidimensional screening plays a significant role in taxation theory, regulation, nonlinear pricing, insurance, etc. Starting from eminent work of Nobel Laureates Mirrlees, Spence and Myerson, there are two main types of generalizations: one is in terms of dimensionality, from one-dimensional to multi-dimensional; the other is in preferences […]

A specific region of the brain, the intra-parietal sulcus (IPS) has reliably been shown, through studies using a variety of methodologies (brain injury, developmental abnormality and neuro-imaging studies), to be a crucial substrate for mathematical competence (Brannon, 2006; Bugden, Price, McLean, & Ansari, 2012; Dehaene, 2004; Dehaene, Piazza, Pinel, & Cohen, 2003; Holloway & Ansari, […]

Reusable plastic crates (RPC’s) are being adopted by the food industry due to the perceived benefits of reduced waste (i.e. paper board), economics and sustainability. However, by reusing crates there is a possibility of distributing contamination from one user to the next if the RPC’s are not sanitized after leaving retailer. Evidence collected over the […]

In order to improve the sustainability of salmonid aquaculture, it is now essential to reduce dietary levels of fish meal by replacement with alternative and terrestrial plant products, and particularly digestible carbohydrates, in the aquafeed formula. However, when fishmeal is substituted at more than 20% by digestible carbohydrates, rainbow trout (Oncorhynchus mykiss), the economically most […]

This proposal introduces a method for finding corresponding regions between 3D shapes automatically. Existing methods require users to provide several point-to-point correspondences, but are not capable of solving correspondence problems when we have a large amount of 3D objects. I propose to resolve the correspondence problem by studying the relationship between functions on shapes, rather […]

Continuous blood pressure (BP) monitoring is highly of assistance for detection of the major public health issue which is cardiovascular problems. Nowadays the BP monitoring technique which are commonly used are mostly using an uncomfortable cuff that makes continuous monitoring impossible since it slows the blood flow. However, measuring continues blood pressures are necessarily and […]

Collision avoidance can be described as a whole-body movement control problem in which visual information is used to elicit accurate movement adaptations. Previous research has demonstrated that children lack knowledge about their own action capabilities as well as the ability to use vision to properly guide actions in static environment. Little is known about how […]

Duchenne muscular dystrophy (DMD) is a severely debilitating and lethal disease affecting approximately 1in 3,500 male births. In a seminal discovery, the Rudnicki lab discovered that deficits in muscle stem cell asymmetric divisions is a part of the underlying mechanism that results in the progressive wasting of skeletal muscles found in DMD. Dystrophin protein, the […]

This project uses computer-based molecular simulations to determine physical and chemical properties of a class of molecules known as alkanolamines dissolved in water designed to absorb carbon dioxide from industrial exit streams. These properties are important in helping select individual alkanolamines to be used as solvents in post-combustion carbon capture and sequestration (CCS). CCS is […]

It is known that music can enhance emotional and verbal communication in individuals who have difficultly doing so. Additionally, it has also been established that music is strongly linked to and can stimulate motor areas in the brain, and may potentially be an interesting aid to motor learning. The overarching goal of the project is […]

Lake size and shape are important factors determining the function and structure of lake ecosystems. Moreover, Lake morphology is important for both biotic and abiotic processes, including species richness of zooplankton, macrophytes, and fishes. In particular, Ontario has tens of thousands of natural ecosystems that make up a large part of Canada’s dominant share ofthe […]