Predictive microsimulation model for knee-OA progression and cost-effectiveness of earlynon-pharmacological therapies to improve long term patient outcomes

The proposed study has three objectives: Objective 1. Develop KOA microsimulation model: To develop and validate a Knee-OA population-based microsimulation model (POHEM-KOA) using the previously developed POHEM-OA model. Objective 2. Perform cost-effectiveness analysis of non-pharmacological therapies for KOA: To use POHEM-KOA in conducting a cost-effectiveness analysis of treatment strategies, including exercise therapy and weight reduction, […]

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Regulation of N-type calcium channel activity by Opioid receptor-like receptor – a novel mechanism to eliminate morphine tolerance

Prolonged morphine treatment is known to cause an up-regulation of ORL1 receptors in the spinal cord (12, 13), which in turn is believed to contribute to the development of morphine tolerance by altering ?-opioid receptor mediate modulation of N-type calcium channels. Indeed, ORL1 antagonists can reverse the development of tolerance, and ORL1 knockout can mediate […]

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Health in HIPPY Homes: Exploring the pathways and barriers to wellbeing of refugee mothers during resettlement and the COVID-19 pandemic, and the role of HIPPY in fostering household health and resilience.

The Health in HIPPY Homes project seeks to explore refugee mothers’ and families’ health during resettlement in Calgary, Alberta, Canada, and the various factors that affect their wellbeing during this period. Additionally, we are interested in better understanding the potential impacts that participating in the Home Instruction for Parents of Preschool Youngsters (HIPPY) program has […]

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Bookkeeper & Funding Research Intern

ASBA is looking to facilitate the current bookkeeping activities at the Zone level by bringing some bookkeeping activities internally. The bookkeeping and funding research intern will also be responsible for assisting in grant and sponsorship research to identify potential funding sources. Part of this process will include to maintain and develop partnerships with potential sponsors […]

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Strategic Communications Officer

Connected Canadians is a non-profit organization that provides older adults with free technology support and training. The COVID-19 pandemic has increased the demand for our services significantly, as our ways of connecting, interacting, and living have shifted online. Connected Canadians has been growing its mentor team significantly to help meet the rising needs of its […]

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Best Practices-Based Standards Development for Digitized and Hands-on Biomanufacturing Training – Advanced Therapies Workforce Development

Demand for biomanufacturing capacity has grown to unexpected levels during the current pandemic and the global vaccine supply shortage. Academic programs provide workers with the necessary background qualifications for employment; however, they are unable to meet the job role-specific requirements for cleanroom-based biomanufacturing under current good manufacturing practices (GMP) necessary for production for patients. This […]

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Plasma-catalytic synthesis of ammonia

A new collaboration with the Chair in Energy Systems at Technical University of Munich and the Catalytic & Plasma Processing Engineering laboratory was established in October 2021 through a successful bilateral-funded project on green plasma-catalytic ammonia synthesis. The main objectives of this initial one-year project is to demonstrate the possibility of integrating a plasma source […]

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Federalism and Politics of Compromise

This study will seek to build a normative theory of compromise and federalism. Several questions will serve as guidelines for our research: If federalism does depend on a specific type of compromise, what kind of compromise are we talking about? Would federalism be a normatively acceptable form of compromise? Several analytical differences will be explored: […]

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Le dialogue interculturel chez Gadamer

Dans notre recherche, nous allons partir de la théorie de la compréhension de Gadamer pour mener une réflexion sur la question du potentiel et des limites du dialogue interculturel, en tant que principe de base du vivre ensemble. L’herméneutique de Gadamer fait ressortir les conditions de base du dialogue interculturel, telles que l’ouverture des participants […]

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Biomechanical Factors as a Diagnostic Aid for Aortic Pathologies

We have developed a software tool that could be used as stand-alone software, or could be implemented in a vascular diagnostic suite (for example within the post-processing software that accompanies most CT and MR scanners). The tool would allow surgeons and radiologists to better evaluate the current state of the aorta under examination and the […]

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