The role of serpin-producing B. longum as an inhibitor of gluten/ATI-related innate immuneactivation

Gluten-related disorders include a variety of clinical entities triggered by the ingestion of gluten containing cereals. The best characterized condition is celiac disease, an autoimmune enteropathy occurring in genetically susceptible individuals. Non-celiac gluten sensitivity or non-coeliac wheat sensitivity (NCGS/ NCWS) is a clinical descriptor of patients, in whom celiac disease and wheat allergy have been […]

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Les défis de l’intégration professionnelle des autistes ayant des compétences clés

L’autisme correspond à un handicap caractérisé par un ensemble de troubles du développement humain qui entraîne des interactions et des communications interpersonnelles inhabituelles et des comportements particuliers. Le taux d’emploi des personnes atteintes d’autisme est très faible alors que leur nombre d’autismes augmente, engendrant des coûts importants pour la société. Toutefois, certains employeurs misent sur […]

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Non-contact vital sign detection of the newborn

Medtronic is a global leader in medical technology and biomedical engineering, working towards non-contact vital signs detection. This technology would be especially helpful in the case of high-risk or premature newborns. Continuous or at least frequent monitoring of newborns outside of clinical environments improves quality of life for parents and newborns recently discharged from the […]

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Non-contact vital sign detection of the newborn – Year two

Medtronic is a global leader in medical technology and biomedical engineering, working towards non-contact vital signs detection. This technology would be especially helpful in the case of high-risk or premature newborns. Continuous or at least frequent monitoring of newborns outside of clinical environments improves quality of life for parents and newborns recently discharged from the […]

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Optical Tissue Imaging DICOM/PACS Integration

The aim of this project is to research and develop a new DICOM modality for the optical coherence tomography images obtained by Perimeter’s Optical Tissue Imaging (OTISTM) device. Following the creation of a suitable modality, a novel solution for transfer to and integration with the PACS servers utilized by current Perimeter customers will also be […]

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Tissue Microstructure of Surgical Specimens depicted with Optical Coherence Tomography

Perimeter Medical Imaging (PMI) has developed an investigational imaging device to aid in achieving clear margins during surgical oncology procedures. This project will employ PMI’s device to image multiple types of human tissues, which have been previously removed during elective or medical procedures. This study will correlate the images obtained using PMI’s device with the […]

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Proof of Principle Application for Biosensors in Animal Models

NXTSens has developed an implantable continuous monitoring, stand-alone and potentially mass-producible microsensor for accurate monitoring of tissue pressure and temperature in damaged limb muscles to better diagnose ACS. The proposed research will involve several sub-projects that include: i) develop appropriate surgical models for the accurate and reproducible placement of the microsensors in rodent compartments; ii) […]

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Novel Cell-surface Engineering Methods to Increase Immune-tolerance of Allogenic Cell Transplantation

Blood transfusion is required for surgery, for the treatment of traumatic accidents and for patients with disorders that require lifelong transfusion therapy. However, when patients receive “mismatched” blood transfusion, their immune system will attack and destroy red blood cells with surface sugars and proteins that differ from their own. This results in massive immune responses […]

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Intervention éducative intermodalitaire au service de la dysphasie

Dysphasie Estrie auprès de la plus grande clientèle de dysphasiques en Estrie. Dès 2017, cet organisme sollicite notre implication au plan de la recherche et développement afin de mieux structurer leur programme d’intervention hebdomadaire (suivi parascolaire) et intensif (camps été). Cette structure est particulièrement modifiée par les données scientifiques, dont les recherches du centre Résodys […]

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Signal Parameter Estimation and Tracking During Atrial Fibrillation Using a Bayesian Time-Delay Estimator

AF is an irregular heart rhythm resulting from abnormal electrical impulses and is the most common cardiac arrhythmia encountered in clinical practice. Ablation therapy has been used to eliminate areas responsible for maintaining the arrhythmia using radiofrequency energy. Targeting the culprit regions usually require accurate estimation of activation times in IEGM recordings. The conventional time […]

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A Computational Modelling Framework for Evaluation of Pandemic Vaccine Strategies

Medicago, a clinical-stage biopharmaceutical company, has the potential to rapidly develop a vaccine in response to a newly sequenced influenza strain, allowing for large-scale vaccination of the population very early during a pandemic. The company would like to know how many doses of vaccine is required and what distribution strategies should be used to maximize […]

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Assessment of the Neonatal Lung Using Structural and Functional MRI

Currently available diagnostic imaging tools, such as chest radiography and computed tomography, are inadequate for assessing the lungs of preterm neonates. There is considerable interest in using magnetic resonance imaging (MRI) to monitor lung development in neonates longitudinally, since it is a non-invasive and non-ionizing imaging modality. MRI can potentially detect complications at an early […]

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