Assessment of the Neonatal Lung Using Structural and Functional MRI – Year two

Currently available medical imaging tools, such as x-rays, are inadequate for assessing the lungs of preterm neonates. There is considerable interest in using magnetic resonance imaging (MRI) to monitor lung development in neonates longitudinally, since it is a non-invasive and non-ionizing imaging modality. MRI can potentially detect complications at an early stage and improve outcomes […]

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Parallel Radiofrequency Transmission Technology for Magnetic Resonance Imaging at 3 Tesla

Funds are requested for one intern to work in the laboratory of Dr. Simon Graham at Sunnybrook Research Institute, Toronto, in partnership with Siemens Healthcare Limited. The intern will work on development of prototype instrumentation that will enable a technique called “parallel radiofrequency transmission (PTX)” to be implemented flexibly for research purposes on a Siemens […]

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Parallel Radiofrequency Transmission Technology for Magnetic Resonance Imaging at 3 Tesla – Year two

Funds are requested for one fellow to work in the laboratory of Dr. Simon Graham at Sunnybrook Research Institute, Toronto, in partnership with Siemens Healthcare Limited. The fellow will work on development of prototype instrumentation that will enable a technique called “parallel radiofrequency transmission (PTX)” to be implemented flexibly for research purposes on a Siemens […]

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Examining the effects of “Fearless Physical Activity” workshops on physiological and psychosocial health in children with congenital heart disease

The “Fearless Physical Activity” workshops are designed to educate and introduce children with congenital heart disease (CHD) to physical activities that are safe for their health. These workshops will provide opportunities for children with CHD and their families to try new activities and to learn about the benefits of lifelong physical activity, specific to those […]

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Developing a Lipid-Based System for Co-delivery of a Vaccine and Adjuvants

University of British Columbia and Amgen British Columbia (ABC) will collaborate to develop a safe and efficient lipid-based vaccine delivery system that can be used in laboratory animals to enhance the production of specific antibodies against difficult targets. These antibodies can be further screened and characterized for treating various diseases in humans.

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Policy implementation through Collective Decision-Making – a case study of a collaborative community-level strategic planning process on immigrant settlement and integration services

The InterCultural Association (ICA) of Greater Victoria leads the establishment of Immigrant and Refugees Canada’s prominent multi-stakeholders strategy named ‘Local Immigration Partnership’ to engage diverse groups to better coordinate, avoid duplication, and enhance the current settlement and integration services aimed at immigrant well-being. This research will observe the process of community-level planning, particularly the development […]

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Examining Vocational Opportunities and Supports for Adults with ASD

The project addresses the under-studied area of vocational service for adults with ASD. The study will implement a mixed method research design consisting of: (1) an environmental scan examining vocational services in Alberta, (2) interviews and/or focus groups with adults with ASD and their caregivers examining their experiences and needs related to vocational supports, and […]

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Effects of dietary glutathione precursors on cellular redox and mitochondrial efficiency in adults consuming a defined hypocaloric diet (Optifast-900; Nestlé Canada)

The aim of the proposed research is to investigate the cellular mechanistic effects of supplementation with a hypocaloric meal replacement product (Optifast-900; Nestlé Canada) containing cysteine and glycine, which are amino acid precursors of the antioxidant glutathione. Impaired cellular glutathione redox normally occurs with aging and metabolic disorders, however, this study will focus on a […]

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Effects of dietary glutathione precursors on cellular redox and mitochondrial efficiency in adults consuming a defined hypocaloric diet (Optifast-900; Nestlé Canada) – Year two

The aim of this research is to investigate the cellular mechanistic effects of supplementation with a hypocaloric meal replacement product (Optifast-900; Nestlé Canada) containing cysteine and glycine, which are amino acid precursors of the antioxidant glutathione. Impaired cellular glutathione redox is evident in obesity and metabolic disorders; Therefore, this study focuses on a population in […]

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Diagnostic Screening for Conscious Awareness in Brain Injury and Disease: Developing the Visual Component

Presently medical personnel do not have adequate tools to assess disorders of conscious awareness after severe brain injury if the patients have difficulty speaking & moving. These people are frequently deemed unresponsive when they may be “in there” but unable to respond. Our research team has developed a rapidly administerable, portable system that measures brain […]

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Evaluation of the CACE Homecare Curriculum

In January 2016, the Centre for Ambulatory Care Education (CACE) at Women’s College Hospital completed the Homecare Curriculum. This online, simulation-based program is designed to help personal support workers, nurses, and rehabilitation professionals provide better care for older adults who wish to stay in their homes. The program presents learners with 3 virtual home environments […]

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Development of new methods for metabolomic screens

In this project we aim to generate simple assays similar to commercial pregnancy tests that can detect the presence of specific molecules (metabolites) related to disease conditions. We will use our knowledge and experience to generate easy-to-use strips that will allow specific detection of health-relevant metabolites that can be used in clinical or at-home settings […]

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