Globally approximately 13.4 million babies are born too early or preterm each year. Many people born preterm, have lung disease causing breathing difficulties, that progresses throughout their lives. This prematurity-associated lung disease is complex and can look very different from person to person, making it harder to diagnose and treat. Some individuals show characteristics that […]

Ce projet de recherche vise à améliorer la prévention des problèmes de santé liés au travail en milieu chaud. Les travailleurs et travailleuses de secteurs comme la construction, l’agriculture, la foresterie ou les services d’urgence sont particulièrement exposés aux vagues de chaleur, qui seront de plus en plus fréquentes avec les changements climatiques. Pour protéger […]

This project is a continuation of my doctoral research, which investigates how IgG antibodies interact with neurons in various neuropathological conditions. So far, we’ve observed that IgGs can be internalized by neurons in models of spinal cord injury, stroke, and neuropsychiatric lupus (NPSLE). The next critical step is to understand the physiological consequences of this […]

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that causes progressive loss of motor neurons, muscle weakness, paralysis, and eventual death. The disease affects males and females differently. A key feature of ALS is immune system dysfunction in the central nervous system (brain and spinal cord) and outside, in peripheral blood. This study aims […]

Healthy pregnancies require major changes in blood flow to support the growing baby. Specifically, the mother’s uterine arteries must widen to allow more blood to reach the placenta, and the placenta must build a complex network of blood vessels to deliver oxygen and nutrients to the fetus. In hypertensive disorders of pregnancy (HDP), these changes […]

Organoids are powerful cellular models that can advance our understanding of human biology and disease progression. They can be generated from human patient samples and be used to screen the best treatment course for patients, thereby allowing for a personalized therapeutic approach. However, a major challenge facing the organoid field is the lack of standard, […]

This research project will explore how certain genetic differences may increase the risk of developing mental health conditions like schizophrenia and bipolar disorder. These conditions often begin in the teenage years or early adulthood, but researchers believe that early brain development, before and after birth, plays a key role. The intern will use powerful computer […]

Severe traumatic brain injury (sTBI) is a leading cause of mortality and disability in pediatric populations. Surviving patients often face long-lasting neurological deficits exacerbated by primary and secondary injury, necessitating further advancements in prognosis and understanding of sTBI mechanisms. Our project aims to address this issue by identifying differentially expressed proteins present in pediatric sTBI […]

Advisory bodies are one of the many ways Toronto City Council and City staff receive input from the public and organizations to address priorities and inform decision-making, policy development and service delivery. This project will assess current approaches to advisory bodies in Toronto and other Canadian municipalities and, through jurisdictional research and participant interviews, identify […]

In Toronto, newly arriving refugee claimants have become the fastest-growing client group in the City’s shelter system, outpacing the rest by far. To support the City of Toronto in identifying effective strategies to address the refugee shelter crisis, Toronto Shelter & Support Services is interested in a comprehensive jurisdictional scan of shelter and housing supports […]

Ce projet vise à implanter une technologie combinant une horloge intelligente et un pilulier connecté et à en évaluer l’impact sur l’autonomie des personnes aînées recevant des soins à domicile. Cette solution, conçue au Québec par la compagnie Eugeria, facilite la prise de médicaments en offrant des rappels visuels et auditifs tout en permettant aux […]

Many patients with mood disorders, which include major depression and bipolar disorder, continue to experience symptoms even after receiving treatment. Traditional research methods have helped improve care but often don’t reflect the realities of clinical practice, which slows progress in applying research to improve services. This project aims to support St. Joseph’s Healthcare Hamilton (SJHH) […]