Protocol amendments of clinical trials protocols in multicenter oncology clinics have a significant impact on their operations. They cause major delays on site activation and patient recruitment. The objective of this project is to evaluate the impact of protocol amendments on site activation timelines and patient recruitment in multicenter oncology clinical trials at Merck and […]

In this project, we aim to build an interactive art sculpture that is intrinsically curious. The sculpture learns by doing some action and observing the consequences. We are interested in studying how people perceive the behaviours emerged form this learning process and how different configuration might change this perception. Moreover, we aim to bring this […]

Le développement de la pharmacogénomique a permis notamment l’identification de biomarqueurs permettant de mieux cibler les patients pouvant bénéficier de certains traitements ou d’estimer le risque d’être éventuellement atteint d’une certaine maladie. Les tests pharmacogénomiques découlant de la découverte de ces biomarqueurs devront être évalués pour leur utilité clinique, mais aussi pour leur impact économique. […]

This project is a component of the Borders in Globalization initiative, an international network of academic partners which is engaged with non-academic organizations that are involved in the study and management of borders and borderlands in Canada and worldwide. The basic goal is to build excellence in the knowledge and understanding of borders. The contribution […]

Ce projet de recherche se concentre sur la conception et la mise en place d’un intranet dans une compagnie pharmaceutique à l’aide d’une approche expérience-utilisateur. « Les intranets sont des systèmes d’information basés sur la technologie du web, qui se positionnent comme des outils favorisant la productivité des employés qui les utilisent et la performance […]

The supervisors and their colleagues have discovered a number of compounds which have greater toxicity towards different tumours than normal cells. The first step in the proposal is to determine the maximum tolerated dose of the compounds in mice after which the candidate anticancer agents will be administered to a special breed of mice in […]

The increased utilization of HVdc technology around the world has created the need for evaluating the reliability of power systems that contains HVdc facilities. For example, if the generation system is remote and it is connected to the load centre through HVdc links, the transmission may have a significant impact on the overall system reliability […]

The overall goal is to create the backend of a mobile personal organizer that suggests professional events (conferences, colloquia, workshops, exhibitions) and contacts to establish while attending events, to members. Currently, the target audience are professionals in the biomedical domain. Given the need to feed data and meta-data from heterogeneous sources into the application, the […]

Healthy ocean food webs are key to the socio-economic viability of coastal communities in British Columbia. The Vancouver Aquarium’s Coastal Ocean Research Institute (CORI) was established in 2014 to provide an ongoing assessment of the health of Canada’s oceans. This project supports this strategic priority of the CORI initiative and advances the organization’s mission to […]

During primary immune responses, dendritic cells (DC) are the principal antigen-presenting cells (APCs) that initiate adaptive immune responses. DCs present pathogenic antigens (such as virus, bacterium and tumour) to induce CD4 and CD8 T cell responses via MHC-I and MHC-II pathways respectively. Recently, our lab has discovered that CD74 molecules not only promote MHC-II but […]

In typical supermarket refrigeration systems, defrosting can account for up to 30% of the total energy consumption of the system while also having an important impact on the quality of the food. To eliminate unnecessary defrost cycles caused by preset time cycle and implement a “defrost on demand” solution, a robust and low cost frost […]

Le Groupe d’experts intergouvernemental sur l’évolution du climat (GIEC) prévoit, suite aux changements climatiques, une augmentation de la fréquence et de l’intensité des précipitations extrêmes. Les impacts de ces bouleversements touchent plusieurs secteurs, dont la sécurité des infrastructures hydrauliques. Dans le but d’améliorer la connaissance sur ces événements et ultimement d’établir des plans d’adaptation, ce […]