Physiological and environmental factors affecting the migratory behavior and survival of sockeye and steelhead salmon smolts

The great number and variety of factors influencing the survival of migrating salmon smolts in the early marine environment makes it difficult to understand the causes of recent declines in smolt survival and salmon population productivity. We will combine novel methodologies (biotelemetry and biomarkers) simultaneously to examine a variety of factors influencing the migratory behaviour […]

Read More
Unseen Enemy: Global Pandemic Knowledge Mobilization

Our deadliest enemies are the ones we cannot see – viruses or bacteria that lurk and mutate, and grow in resistance, until they become an unstoppable pandemic. This year four interns will work alongside the Tech Samurais company to produce key communication tools that will make effective interventions into the Canadian and global conversation about […]

Read More
Generation of new lead compounds with drug-like properties by derivatization of existing drugs

Access to efficient drugs to treat diseases that affect Canadians is among the highest priorities of our society. The development of new medicinal agents depends on the access to small molecules capable of interacting with biological targets associated with those diseases. These small molecules are typically identified by screening large collections of synthetic compounds. Paraza […]

Read More
Exome Annotator: Developing a system biology approach to genome annotation for disease risk assessment

Understanding the underlying factors that cause inherited diseases to develop is an important step in improving the health status of individuals, and identifying effective prevention and control measures. This project aims to apply fundamental knowledge of genetics, genome sequence analysis, modeling and simulations, and bio-informatics to uncover the relationship between these factors and assess the […]

Read More
Accurate Proximity Sensing for Avionic Systems

This project targets the design of a highly accurate proximity sensing system that is capable of operating in a wide distance range under wide variations in temperature and for different sensor characteristics. The system is based on passive inductive proximity sensors that can withstand harsh environments, and, therefore, are widely used in avionic applications. Our […]

Read More
Methods for detecting Hardware Blu-ray player emulation, debugging or instrumentation

Blu-Ray Disk Framework offers content protection system which is intended to protect audio/video media against piracy. The Blu-Ray Content Protection System consists of three individually working components: Advance Access Control System, ROM-Mark and BD+. Each component works collaboratively with the other in order to protect high-definition content distributed on Blu-Ray discs. The ability of a […]

Read More
Investigation and development of plasma-based cancer diagnostic

The blood of cancer patients contains DNA that has been shed by their tumours (circulating tumour DNA or ctDNA). As such, any genetic mutations in the tumour may be detected in the patient’s blood. Theoretically, patients can be followed and monitored through analysis of ctDNA, which would reveal if the patient is responding to treatment, […]

Read More
Development of novel biochemical and biophysical assays for the identification of inhibitors of Hypoxia Inducible Factor-2

Cancer cells are known for their unique capacity to survive and grow in a low oxygen tension environment in the middle of a poorly vascularized solid tumor. This adaptation, which is central to the tumorigenesis process, is mediated by precise cellular mechanisms allowing the regulation of gene expression. Thus, the development of small molecules to […]

Read More
Penetration of diluted bitumen on shorelines in the event of a marine spill

The goal of this research is to create a knowledge tool that can assist responders to act quickly and effectively in the event of a marine oil spill. In order to accomplish this goal, we will (1) develop a simple field test to gauge shoreline permeability in relation to stranded diluted bitumen on natural shorelines; […]

Read More
Healthy Obesity through Fitness

Rates of obesity are continuously rising despite efforts to decrease them. The purpose of this study is to show that obese but fit individuals are protected from many adverse health conditions such as metabolic syndrome, insulin resistance, type-2 diabetes, high blood pressure, and cardiovascular disease as the result of being physically active. This study is […]

Read More
GPU Performance Auto-tuning Using Machine Learning

Optimizing a program for Graphics Processing Units (GPUs) is critical for performance, yet remains a challenge due to the non-intuitive interactions among the optimizations and the GPU architecture. Automatic optimization tuning for a GPU is demanding particularly given the exploding number of mobile GPU variants in the market. We explore the use of machine learning […]

Read More