An investigation on software quality measurement

Software failure may result in substantial damage, especially to human life and financial loss. High-quality software is recognized as a product that has been specified correctly, and that meets its expected specifications. It is important that the quality characteristics be specified, measured and evaluated. The primary objective of this investigation is to create the software […]

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Cross-sector partnerships for implementing sustainable community plans: comparison between a Canadian city and international communities to determine drivers for partners to remain in the partnerships

The project involves the identification of a Canadian community to be compared with Barcelona (Spain), Bristol (UK) and other two international communities, all experienced cities on sustainability with more than 100 partners including businesses, NGOs, academia and the public sector. The Canadian community must comply with certain criteria to make findings comparable with the international […]

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Identification of early events involved in RNA disruption in order to improve its utility as a chemotherapy response and prognostic biomarker

It is not well known that the majority of breast cancer patients do not receive a survival benefit from chemotherapy. Yet, they experience many negative short- and long-term side effects from chemotherapy. This is also the case for other cancers. There is thus a clear, unmet need for a diagnostic tool that can reliably identify […]

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A new paradigm for the discovery of anti-cancer drugs based on tumour RNA disruption

While chemotherapy drugs are effective in combating tumour growth in cancer patients, many such drugs permit the development of drug-resistant tumours and progression of the disease. We have observed that several chemotherapy agents induce the degradation of tumour cell ribonucleic acid (RNA) in the laboratory and in cancer patients. We have further shown that this […]

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Intraoperative optical characterization of brain tumor tissues

The goal of neurosurgery are two folds, 1) to achieve maximal resection of the target lesions, but simultaneously 2) minimize damage to adjacent healthy brain tissues. Currently surgeons rely on preoperative images such as Magnetic Resonance Imaging to define tumor boundaries. However, the accuracy of such images decreases intraoperatively due to brain shift. For these […]

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Development of negamycin, a novel class of antibiotic for Gram-negative bacterial infections

Antimicrobial resistance threatens effective prevention and treatment of microbial infections. Over two million hospitalized patients acquire infection from antimicrobial resistant microbes resulting in more than 23,000 deaths in North America. Therefore, development of a novel class of antimicrobials is in urgent need. The goal of our research project is to develop a novel antibiotic for […]

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Developing Energy-Efficient HVAC-R Systems for Smart Buildings

AYO Smart Home Ltd. is pursuing the development of integrated energy management technologies for smart buildings. Various approaches such as heat recovery, solar energy, energy storage, and passive cooling are being investigated by the AYO Smart Home Ltd. company. Novel technologies for Heating, Ventilating, Air-Conditioning, and Refrigeration (HVAC-R) are also considered as a crucial part […]

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Dopamine Receptor Imaging in Dementia Using Hybrid PET/MRI

Although life expectancy is increasingly associated with the treatment of heart disease and cancer, there has been virtually no improvement in life expectancy for patients with dementia. Dementia has a devastating impact to the patient, family members and society because patients become dependent on family caregivers, who are then less productive in other aspects of […]

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Analysis, development and implementation of virtual and face-to-face mechanisms and tools to stimulate coordination, exchange and collaboration between members of a community of entrepreneurs

This project seeks to perform an analysis about the dynamics of interactions between members of an entrepreneurship community. Entrepreneur’s behaviors will be compared with the literature on knowledge transfer and concepts about entrepreneur’s thinking. Using data collected within the entrepreneur community and concepts, the intern will define the parameters needed for the development of effective […]

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Intracellular growth of Mycobacterium tuberculosis: prospects for drug discovery

The success of Mycobacterium tuberculosis (Mtb), the infectious agent of tuberculosis (TB), lies in its ability to primarily infect, reside, and multiply in the lungs of patients. Mtb infects white blood cells termed alveolar macrophages and hides from the host immune response as well as from many antibiotics used for treatment, creating additional challenges for […]

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