Development of a new generation of neurovascular device for the treatment of fusiform cerebral bifurcation aneurysms using CFD modeling and virtual simulation of stent crimping into a catheter – Year two

Cerebral aneurysm (CA), is an abnormal dilation of the cerebral arterial wall, which accounts for more than half a million deaths each year worldwide. Flow diverters (FDs) represent one method recently developed in treating CAs. Typically, they do not need coiling (releasing platinum micro-coils within the aneurysm) and act purely to prevent substantial blood inflow […]

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Evaluation of the implementation at scale of a public health intervention to promote social and emotional development in the early years in British Columbia

British Columbia’s Ministry of Mental Health and Addictions has identified healthy social and emotional development (SED) in early childhood as a priority action towards addressing the province’s mental health crisis. In response, ChildHealth BC (CHBC) is developing a multi-component provincial intervention to expand the capacity of caregivers to promote SED in young children- the first […]

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Comprehensive Molecular Analysis of Pre- and Postmenopausal Human Mammary Cells to Enable Their Optimized Growth as Organoids Ex Vivo

The goal of this project is to discover new factors essential for maintaining a normal human mammary gland. The approach is to generate and analyze in depth the protein-encoding RNAs and chromatin states that control their expression in the different types of cells that constitute the human mammary epithelium and its surrounding stromal cells. This […]

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Comprehensive Molecular Analysis of Pre- and Postmenopausal Human MammaryCells to Enable Their Optimized Growth as Organoids Ex Vivo – Year two

The goal of this project is to discover new factors essential for maintaining a normal human mammary gland. The approach is to generate and analyze in depth the protein-encoding RNAs and chromatin states that control their expression in the different types of cells that constitute the human mammary epithelium and its surrounding stromal cells. This […]

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Ensuring Stability and Accuracy of Multi-rate Electromagnetic Transient Simulation

Real-time digital power system simulators are used for testing and debugging control equipment intended for field installation. They simulate the power network in ‘real-time’, i.e., the simulation computations are rapidly completed so as to retain synchronism with a real-world clock. This requires the level of complexity in different components of the network to be judiciously […]

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Synthesis and modeling of stimuli-responsive polymers for fracturing fluids use

Currently, the global warming alerts, oil prices fluctuations and clean energy have paved the way of investing in the producing wells by enhancing the recovery of hydrocarbons compared to exploration wells. Applying hydraulic fracturing from injected fluids is most common method used. These fluids create cracks in the bedrock and push the hydrocarbons to the […]

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Segmentation automatique de dents à partir des scans oraux

L’automatisation des tâches de fabrication dans les laboratoires de prothèses dentaires revêt un intérêt considérable, à la fois pour les techniciens et pour les patients. En effet, une partie importante du travail consiste en des tâches répétitives, longues et qui exigent un effort de concentration et de minutie soutenu. Par conséquent, il existe une grande […]

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Research in Support of New Orthotropic Steel Bridge Deck Provisions for CSA S6:25

Orthotropic bridge deck is lightweight steel deck, typically fabricated by welding “ribs” to the underside of a flat steel plate. The potential benefits of these deck systems are compelling. For example, from 1991 to 1993, the deteriorating deck on the Champlain Bridge was replaced with orthotropic steel deck panels weighing 25% less than the original […]

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Mass spectrometry for multiplexed highthroughput analysis of large molecules

Whether it is for research, development or diagnostics, life sciences typically require the quantitation and characterization of samples with assays that classically measure molecules one at a time. Considering that the development and execution of such assays are time consuming and requires considerable investment, the uses of multiplexed analysis would be highly advantageous. Mass spectrometry […]

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Characterizing anti-inflammatory properties of medicinal mushrooms

Medicinal mushrooms possess compounds with beneficial properties, including anti-microbial, anti-tumoral, and anti-inflammatory, which support their role and application in current healthcare practices. In this proposal, we will measure the impact and role of extracts from medicinal mushrooms provided by Wake Network Inc. to identify how immune cells and an animal model change their response to […]

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Powering Transactive Energy Markets using Smart Contracts in an Integrated IoT-Blockchain Platform

In this project, we propose the use of blockchains to provide reliability, security, and transparency for collecting and querying IoT data in the energy sector. In particular, we will implement and evaluate our blockchain solution for enabling transactions in local energy markets, where homeowners have the capacity to generate energy (through renewables), stock energy (through […]

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