Since 1960, System engineering has been used as an approach for multidisciplinary and concurrent design of complex systems. It relies on a system-centered thinking to solve problems and different design process models have been used for system engineering such as V-model. Model-based System engineering (MBSE) was developed to replace documents with models. AIS is developing […]

Biofouling is the process where marine organisms adhere to surfaces used in aquaculture and marine applications, such as tanks, netting, plumbing, and hull surfaces. The additional weight and drag on surfaces and narrowing of openings in netting or plumbing strongly affect energy costs and efficiency of operations. Conventional anti-biofouling coatings contain tin or copper, which […]

The interns for this proposed project will work under the supervision of Dr. Thompson to extend our understanding of the health risks associated with different modes of administration and investigate sex and gender differences in cannabis use, practices, effects, and outcomes. Identifying indicators of negative health outcomes is an important step in developing effective cannabis […]

Over the last several decades, challenges in the development, production, supply, and use of vaccines have been raised and by consequence had led to increasing concern around the world. As a result, an increase in research and innovation in the vaccine industry is needed. In this sense, one of the most critical factors in the […]

Obtaining accurate images of the spine is important for different medical purposes. For example, to measure how deformed the spine is in patients with scoliosis and select the most suitable treatment. Images can also be used to guide a clinician while inserting a needle to reach a exact location in the spine to administer anesthesia. […]

Single domain antibodies (sdAbs) represent a versatile class of heavy chain antibodies lacking a paired light chain and encoded by VHH germline genes typically expressed in camelids. KisoJi Biotech has developed a transgenic mouse line in which each mouse expresses multiple camelid VHH genes capable of specifically binding any antigen of interest. The small molecular […]

Single domain antibodies (sdAbs) represent a versatile class of heavy chain antibodies lacking a paired light chain and encoded by VHH germline genes typically expressed in camelids. KisoJi Biotech has developed a transgenic mouse line in which each mouse expresses multiple camelid VHH genes capable of specifically binding any antigen of interest. The small molecular […]

A wide range of cognitive faculties are commonly compromised in numerous trauma-exposed populations, leading to impaired functioning, and reduced treatment response rates. There is a dire need for novel therapies that can directly target such deficits in top-down cognitive control. Goal management training (GMT) is one such cognitive remediation therapy found to be effective for […]

Imaging of cerebral perfusion (the delivery of blood to a capillary bed in the brain tissue) is significant for diagnosing a variety of diseases. There are multiple challenges associated with perfusion imaging which significantly limits the quality of cerebral perfusion images. I am planning to develop a novel approach of cerebral perfusion magnetic resonance imaging […]

Immunotherapies are transforming conventional cancer treatments with significant improvement of patient survival rates. FDA-approved immunotherapies (immune checkpoint inhibitors, ICIs) have shown remarkable success in the treatment of hematologic malignancies but very low response rate in patients with solid tumors. Therefore, there is an urgent need for novel therapies against solid malignancies. Cura Therapeutics is developing […]

To combat the degradation of receiving water resulting from stormwater runoff approaches that focus on retaining and infiltrating stormwater at the source, referred to as Low Impact Development (LID) practices, are being proposed more frequently in recent years. Toronto and Region Conservation Authority recently initiated monitoring of precipitation and runoff from a large industrial site, […]

Cerebral aneurysm (CA), is an abnormal dilation of the cerebral arterial wall, which accounts for more than half a million deaths each year worldwide. Flow diverters (FDs) represent one method recently developed in treating CAs. Typically, they do not need coiling (releasing platinum micro-coils within the aneurysm) and act purely to prevent substantial blood inflow […]