The development of monoclonal antibodies for early diagnosis and therapeutic application in Alzheimer’s disease

Alzheimer’s disease is the most common neurodegenerative disorder. The recent immunotherapy brings the hope of treating AD as suggested by several preclinical studies. This project first aims to develop a humanized monoclonal antibody to target the molecules involved in generating a toxic protein of AD, named amyloid ?, and test the application of this antibody […]

Read More
In vitro validation of candidate therapeutic targets for Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, which is characterized by shortness of breath and progressive loss in lung function, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. Therefore, there is a pressing […]

Read More
Text Recognition Software Development for Legal Services

The rapid advancement in the areas of machine learning and artificial intelligence has led to many breakthroughs in industries. As an online medium legal intermediary platform, Right Legal aims to connect clients and lawyers by providing them with a secure, convenient, and efficient platform. In order to accomplish this, we take into account of (1) […]

Read More
Chemical and biological characterization of the non-tetrahydrocannabinoid profiles of medicinal plants

We propose to perform detailed studies that characterize chemically and biologically and the unaltered ancestral plant species of the Cannabis genus. Chemically, these studies will provide the chemotype profiles for each parental species for a spectrum of non-tetrahydrocannabinoid compounds. Biologically, these studies will provide the pharmacological profiles for each parental species in conjunction with the […]

Read More
High value-addition of forestry residuals into levulinic acid

Levulinic Acid (LA) is among the top twelve value-added platform chemicals, and is an abundant and versatile building block for numerous compounds aimed at consumer applications. LA is produced in insufficient quantities to meet market demand and by using fossil fuels which prevents LA production to meet environmental standards. We propose a novel, efficient, and […]

Read More
Étude de la génomique des levures Brettanomyces pour la caractérisation et la classification des différentes souches selon leur potentiel brassicoles

L’utilisation des Brettanomyces au sein des fermentations alcooliques est en forte croissance depuis plusieurs années. Traditionnellement considérée comme un contaminant, cette levure se retrouve désormais au centre de nombreux produits fermentés, particulièrement dans l’industrie brassicole. Jusqu’à maintenant, les Brettanomyces sont utilisées principalement en fermentation secondaire, afin d’affiner les produits. Par contre, peu d’informations sont connues […]

Read More
Climate change and water use: can increased diversity help protect forests?

Forests provide habitat to more than 65% of terrestrial biodiversity, yet are being eliminated or greatly simplified at an alarming rate under global change (GC). Current forestry practices tend to favour a handful of species, without considering resilience of resulting forests to GC. During the past two decades, studies have investigated the complex relationships between […]

Read More
Outils d’aide à la décision pour la planification et la prestation des soins et des services à domicile

Dans ce projet, nous proposons le de?veloppement d’outils d’aide a? la de?cision novateurs pour ame?liorer la prestation des soins et des services a? domicile. Le projet est articule? autour de deux principaux sujets de recherche : A) le de?veloppement d’approches d’optimisation pour la gestion de l’offre (les soignants) et de la demande (les patients); et […]

Read More
Design and optimization of topography based customizable mini-scleral contact lenses

Cornea disorder diseases, like keratoconus, are characterized by progressive thinning and distortion of the apical cornea that leads to complex optical aberrations due to either irregular astigmatism or corneal scarring. For patients with irregular cornea, corneal contact lenses no longer fit and become intolerable with discomfort. In such cases, scleral and mini-scleral (MS) contact lenses […]

Read More