Multiplexed confocal FLIM microscope for Drug Discovery

Fluorescence lifetime imaging (FLIM) is an emerging technique that is used drug discovery by universities and pharmaceutical companies. The research team developed a multiplexing technique that can improve the imaging speed by 1000 times. However, matching 1000 focal points to 1000 detectors individually is very difficult. In this project, the team plans to develop a self-adaptive online alignment technology that can optimize the alignment between the 1000 point foci array and the detector array. Successful of the proposed development will significantly strengthen the technology and pave the path towards a startup or joint venture for the next phase commercialization activities with the industry partner.

Faculty Supervisor:

Qiyin Fang

Student:

Morgan Richards

Partner:

Lumen Instruments

Discipline:

Engineering - biomedical

Sector:

Manufacturing

University:

McMaster University