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Dental caries is a major health hazard in the general population worldwide. Fluoride-based formulations are conventionally used to resolve this problem but they present certain important disadvantages, which has been overlooked. Here we propose to develop and characterize a non-fluoride based dental varnish using natural product conjugated nanoparticles that holds the potential of inhibiting bacterial plaque formation and repair early damage on tooth surface. The potential long-term benefits of this product are extensive and include prevention of dental caries and improved quality of life. The nano-varnish is inexpensive, fast and simple to use, which can be used by dentists/individuals with minimum learning curve. The varnish fills the unmet medical need for patients with high caries risk, particularly children.
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